A Study to Investigate Intravenous Tocilizumab in Participants With Moderate to Severe COVID-19 Pneumonia
Public ClinicalTrials.gov record NCT04363736. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase-II, Open-Label, Randomized, Multicenter Study to Investigate the Pharmacodynamics, Pharmacokinetics, Safety, and Efficacy of 8 mg/kg or 4mg/kg Intravenous Tocilizumab in Patients With Moderate to Severe COVID-19 Pneumonia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will assess the pharmacodynamics, pharmacokinetics, safety and efficacy of two different doses of tocilizumab (TCZ) in combination with standard-of-care (SOC) in hospitalized adult participants with moderate to severe COVID-19 pneumonia.
Study identification
- NCT ID
- NCT04363736
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 97 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 4, 2020
- Primary completion
- Aug 11, 2020
- Completion
- Aug 11, 2020
- Last update posted
- Aug 30, 2022
2020
United States locations
- U.S. sites
- 24
- U.S. states
- 15
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic - Arizona | Phoenix | Arizona | 85054 | — |
| St. Jude Medical Center | Fullerton | California | 92835 | — |
| LAC + USC Medical Center | Los Angeles | California | 90033 | — |
| USC Keck Medical Center of USC | Los Angeles | California | 90033 | — |
| Norwalk Hospital | Norwalk | Connecticut | 06856 | — |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Mayo Clinic | Jacksonville | Florida | 32224 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Advocate Lutheran General Hospital | Park Ridge | Illinois | 60068 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Renown Institute for Heart & Vascular Health | Reno | Nevada | 89502 | — |
| St Joseph's Regional Medical Center | Wayne | New Jersey | 07470 | — |
| SUNY Downstate Medical Center. | Brooklyn | New York | 11203 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Mercy St. Vincent Medical Center | Toledo | Ohio | 43608 | — |
| Lehigh Valley Health Network | Allentown | Pennsylvania | 18103 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Allegheny Health Network (Pittsburg PA) | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Michael E. DeBakey VA Medical Center | Houston | Texas | 77030 | — |
| Houston Methodist Sugar Land Hospital | Sugar Land | Texas | 77479 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04363736, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 30, 2022 · Synced Sep 27, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04363736 live on ClinicalTrials.gov.