A Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Participants With COVID-19 Pneumonia
Public ClinicalTrials.gov record NCT04372186. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tocilizumab in Hospitalized Patients With COVID-19 Pneumonia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study (EMPACTA) will a) evaluate the efficacy and safety of tocilizumab (TCZ) compared with a placebo in combination with standard of care (SOC) in hospitalized participants with COVID-19 pneumonia, and b) include an optional long-term extension for eligible participants to explore the long-term sequelae of resolved COVID-19 pneumonia.
Study identification
- NCT ID
- NCT04372186
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 377 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 14, 2020 (Actual)
- Primary completion
- Aug 18, 2020 (Actual)
- Completion
- Sep 22, 2020 (Actual)
- Last update posted
- Feb 10, 2023
2020
United States locations
- U.S. sites
- 32
- U.S. states
- 14
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner - University Medical Center Phoenix; In-Patient Pharmacy | Phoenix | Arizona | 85006 | — |
| Univ of AZ Coll of Med | Tucson | Arizona | 85724 | — |
| El Centro Regional Medical Center | El Centro | California | 92243 | — |
| eStudySite | La Mesa | California | 91942 | — |
| Highland Hospital Oakland | Oakland | California | 94602 | — |
| St. Joseph'S Hospital | Orange | California | 92563 | — |
| San Leandro Hospital; Inpatient Pharmacy | San Leandro | California | 94578 | — |
| Larkin Community Hospital Palm Springs Campus (Hialeah) | Hialeah | Florida | 33012 | — |
| Miami Veterans Administration Healthcare System - NAVREF | Miami | Florida | 33125 | — |
| University of Miami Pulmonary | Miami | Florida | 33125 | — |
| Larkin Community Hospital | South Miami | Florida | 33143 | — |
| St. Lukes Boise Medical Center | Boise | Idaho | 83712 | — |
| Ochsner Clinic | New Orleans | Louisiana | 70121 | — |
| Holy Cross Germantown Hospital | Germantown | Maryland | 20876 | — |
| Holy Cross Hospital | Silver Spring | Maryland | 20910 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| St. Joseph'S Regional Medical Center | Paterson | New Jersey | 07503 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| SUNY Downstate Medical Center. | Brooklyn | New York | 11203 | — |
| Elmhurst Hospital Center | Elmhurst | New York | 11373 | — |
| Flushing Hospital | Flushing | New York | 11355 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| Harlem Hospital | New York | New York | 10037 | — |
| Canton-Potsdam Hospital | Potsdam | New York | 13676 | — |
| St. Barnabas Hospital | The Bronx | New York | 10457 | — |
| Novant Health Presbyterian Medical Center (Presbyterian Hospital) | Charlotte | North Carolina | 28204 | — |
| Cape Fear Valley Medical Center | Fayetteville | North Carolina | 28304 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Valley Baptist Medical Center | Harlingen | Texas | 78550 | — |
| Michael E Debakey VA Medical Center | Houston | Texas | 77030 | — |
| McAllen Medical Center | McAllen | Texas | 78503 | — |
| Sentara Medical Group | Virginia Beach | Virginia | 23462 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04372186, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 10, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04372186 live on ClinicalTrials.gov.