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Completed Phase 2 Interventional Results available

Convalescent Plasma to Limit SARS-CoV-2 Associated Complications

ClinicalTrials.gov ID: NCT04373460

Public ClinicalTrials.gov record NCT04373460. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Comparison of the Efficacy and Safety of Human Coronavirus Immune Plasma (HCIP) vs. Control (SARS-CoV-2 Non-immune) Plasma Among Outpatients With Symptomatic COVID-19

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To assess the efficacy and safety of Human coronavirus immune plasma (HCIP) to reduce the risk of hospitalization or death, the duration of symptoms and duration of nasopharyngeal or oropharyngeal viral shedding.

Study identification

NCT ID
NCT04373460
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Johns Hopkins University
Other
Enrollment
1,225 participants

Conditions and interventions

Conditions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 3, 2020 (Actual)
Primary completion
Jan 14, 2022 (Actual)
Completion
Dec 14, 2022 (Actual)
Last update posted
Jun 2, 2023

2020 – 2022

United States locations

U.S. sites
29
U.S. states
16
U.S. cities
27
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
Center for American Indian Health - Chinle Office Chinle Arizona 86503 —
Mayo Clinic, Phoenix Phoenix Arizona 85054 —
University of Arizona, Phoenix Tucson Arizona 85719 —
University of Arizona, Tuscon Tucson Arizona 85724 —
Center for American Indian Health - Whiteriver Office Whiteriver Arizona 85941 —
University of California, Los Angeles Los Angeles California 90095 —
University of California, Irvine Health Orange California 92868 —
Western Connecticut Health Network, Danbury Hospital Danbury Connecticut 06810 —
Western Connecticut Health Network, Norwalk Hospital Norwalk Connecticut 06856 —
University of Miami Coral Gables Florida 33124 —
University of Miami Clinical Translational Research Site Miami Florida 33136 —
NorthShore University HealthSystem Evanston Illinois 60201 —
Tulane University New Orleans Louisiana 70112 —
Anne Arundel Medical Center Annapolis Maryland 21401 —
The Johns Hopkins University Baltimore Maryland 21205 —
MedStar Washington Hospital Center Hyattsville Maryland 20782 —
University of Massachusetts Worcester Worcester Massachusetts 01655 —
Wayne State University Detroit Michigan 48202 —
University of New Mexico Health Sciences Center Albuquerque New Mexico 87131 —
Center for American Indian Health - Gallup Office Gallup New Mexico 87301 —
Center for American Indian Health - Shiprock Office Shiprock New Mexico 87420 —
Vassar Brothers Medical Center Poughkeepsie New York 12601 —
University of Rochester Rochester New York 14642 —
University of Cincinnati Medical Center Cincinnati Ohio 45219 —
Lifespan/BrownUniversity (Rhode Island Hospital) Providence Rhode Island 02903 —
Baylor College of Medicine Houston Texas 77030 —
University of Texas Health Science Center at Houston Houston Texas 77030 —
The University of Utah Salt Lake City Utah 84132 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04373460, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 2, 2023 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04373460 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →