Prospective Study to Assess Disease Activity and Biomarkers in Minority Participants With Relapsing Multiple Sclerosis (RMS) After Initiation and During Treatment With Ocrelizumab
Public ClinicalTrials.gov record NCT04377555. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Prospective, Single-arm, Multi-center Study to Assess Disease Activity and Biomarkers of Neuronal Damage in Minority Patients With Relapsing Multiple Sclerosis Receiving Treatment With Ocrelizumab
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Open-label, prospective, single-arm, multi-center study to assess disease activity and biomarker of neuronal damage in minority patients (self-identified Black or African American (AA) and Hispanic/Latino (HA) patients with relapsing multiple sclerosis (RMS) receiving treatment with Ocrelizumab. The study plans to enroll approximately 150 participants (75 AA and 75 HA) with 50 participants enrolled in a CSF sub-study.
Study identification
- NCT ID
- NCT04377555
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 179 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 30, 2020 (Actual)
- Primary completion
- Dec 15, 2022 (Actual)
- Completion
- Nov 11, 2025 (Actual)
- Last update posted
- Feb 4, 2026
2020 – 2025
United States locations
- U.S. sites
- 26
- U.S. states
- 18
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Keck School of Medicine of USC | Los Angeles | California | 90033-5315 | — |
| Georgetown University Medical Center | Washington D.C. | District of Columbia | 20007 | — |
| Baptist Neurology - Beaches | Jacksonville Beach | Florida | 32250 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136 | — |
| Shepherd Center Inc. | Atlanta | Georgia | 30309 | — |
| Atlanta Neuroscience Institute | Atlanta | Georgia | 30327 | — |
| Rush University Medical Center | Chicago | Illinois | 60612-3244 | — |
| University of Chicago | Chicago | Illinois | 60637 | — |
| Josephson Wallack Munshower Neurology PC | Indianapolis | Indiana | 46256 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201-1642 | — |
| Johns Hopkins University Neurology Research Office | Baltimore | Maryland | 21287 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Hackensack University Medical Center | Paramus | New Jersey | 07652 | — |
| SUNY Upstate Medical Center | Syracuse | New York | 13210 | — |
| Guilford Neurologic Research Partners, LLC | Greensboro | North Carolina | 27401 | — |
| Jefferson University Hospitals, Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Neurology Clinic - Cordova | Cordova | Tennessee | 38018 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37204 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| North Texas Institute of Neurology and Headache NextStage Clinical Research Clinic | Frisco | Texas | 75034 | — |
| Baylor College of Medicine Medical Center | Houston | Texas | 77030 | — |
| Multiple Sclerosis Center of Tidewater | Norfolk | Virginia | 23502 | — |
| Wheaton Franciscan Healthcare - St. Francis Outpatient Center | Milwaukee | Wisconsin | 53215 | — |
| Froedtert and The Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04377555, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 4, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04377555 live on ClinicalTrials.gov.