Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

ClinicalTrials.gov ID: NCT04380740

Public ClinicalTrials.gov record NCT04380740. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 12:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Double-Blind Trial of Abatacept Extended Dosing Versus Abatacept Short-term Dosing for Graft Versus Host Disease Prophylaxis: "ABA3"

Study identification

NCT ID: NCT04380740
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Boston Children's Hospital; Other
Enrollment: 160 participants

Conditions and interventions

Conditions

Graft Vs Host Disease

Interventions

Abatacept Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 2 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Mar 29, 2022
Primary completion: Apr 30, 2027
Completion: May 31, 2028
Last update posted: May 10, 2026

2022 – 2028

United States locations

U.S. sites: 15
U.S. states: 11
U.S. cities: 11

Facility	City	State	ZIP	Site status
City Of Hope National Medical Center	Duarte	California	91010	Active, not recruiting
Moffitt Cancer Center	Tampa	Florida	33612	Active, not recruiting
Emory University/Winship Cancer Center	Atlanta	Georgia	30322	Active, not recruiting
Children's Healthcare of Atlanta	Atlanta	Georgia	30329	Recruiting
University of Chicago	Chicago	Illinois	60637	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Active, not recruiting
Boston Children's Hospital	Boston	Massachusetts	02115	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Active, not recruiting
Dana-Farber Cancer Institute	Boston	Massachusetts	02215	Active, not recruiting
University of Michigan	Ann Arbor	Michigan	48109	Active, not recruiting
Washington University St. Louis	St Louis	Missouri	63110	Withdrawn
University of Rochester	Rochester	New York	14642	Recruiting
Cincinnati Children's Hospital	Cincinnati	Ohio	45229	Active, not recruiting
Oregon Health and Sciences University	Portland	Oregon	97239	Active, not recruiting
Children's Hospital of Philadelphia	Philadelphia	Pennsylvania	19104	Withdrawn

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04380740, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 10, 2026 · Synced May 20, 2026

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The complete protocol, eligibility criteria, and contact information for NCT04380740 live on ClinicalTrials.gov.

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