A Study of AK104, a PD-1/CTLA-4 Bispecific Antibody in Subjects With Recurrent/Metastatic Cervical Cancer
Public ClinicalTrials.gov record NCT04380805. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Single Arm, Open Label Study to Evaluate the Efficacy and Safety of AK104 in Subjects With Recurrent or Metastatic Cervical Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2, global, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic cervical carcinoma.
Study identification
- NCT ID
- NCT04380805
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 30 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 14, 2020
- Primary completion
- Dec 21, 2022
- Completion
- Jan 30, 2023
- Last update posted
- Feb 27, 2025
2020 – 2023
United States locations
- U.S. sites
- 19
- U.S. states
- 12
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Womens Cancer Research Foundation | Newport Beach | California | 92663 | — |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| BRCR Medical Center | Plantation | Florida | 33322 | — |
| Augusta University Medical Center | Augusta | Georgia | 30912 | — |
| Illinois Cancer Specialists | Arlington Heights | Illinois | 60005-2380 | — |
| Maryland Oncology Hematology (Plum Orchard) | Silver Spring | Maryland | 20904 | — |
| Monter Cancer Center | Lake Success | New York | 11042 | — |
| The Blavatnik Family - Chelsea Medical Center at Mount Sinai | New York | New York | 10011 | — |
| Oncology Hematology Care Inc | Cincinnati | Ohio | 45242 | — |
| Oklahoma Cancer Specialists and Research Institute, LLC | Tulsa | Oklahoma | 74146 | — |
| Chattanooga's Program In Women's Oncology | Chattanooga | Tennessee | 37403 | — |
| Tennessee Oncology - Centennial Clinic | Nashville | Tennessee | 37203 | — |
| University of Texas Southwestern | Dallas | Texas | 75390 | — |
| Texas Oncology-Fort Worth Cancer Center | Fort Worth | Texas | 76104 | — |
| Lyndon B. Johnson Hospital (MD Anderson) | Houston | Texas | 77026 | — |
| Texas Oncology (Woodlands) | The Woodlands | Texas | 77380 | — |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Pacific Gynecology Specialists, P. C. | Seattle | Washington | 98104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 6 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04380805, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 27, 2025 · Synced Sep 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04380805 live on ClinicalTrials.gov.