A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19
Public ClinicalTrials.gov record NCT04380961. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical COVID-19 Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the clinical response of sirukumab (administered as a single intravenous dose) plus standard of care (SOC) compared to placebo plus SOC in COVID-19.
Study identification
- NCT ID
- NCT04380961
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 212 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years to 84 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 24, 2020 (Actual)
- Primary completion
- Apr 9, 2021 (Actual)
- Completion
- Jun 24, 2021 (Actual)
- Last update posted
- Jun 21, 2022
2020 – 2021
United States locations
- U.S. sites
- 16
- U.S. states
- 11
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MemorialCare Research Miller Children's and Women's Hospital Long Beach | Long Beach | California | 90806 | — |
| Hoag Memorial Hospital | Newport Beach | California | 92663 | — |
| Holy Cross Hospital - Michael and Dianne Bienes Comprehensive Cancer Center | Fort Lauderdale | Florida | 33308 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| University of Illinois College of Medicine at Peoria | Peoria | Illinois | 61637 | — |
| Louisiana State University Health Sciences Center | New Orleans | Louisiana | 70012 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| Beaumont Health Systems | Royal Oak | Michigan | 48073 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Saint Michaels Medical Center - Infectious Disease | Newark | New Jersey | 07102 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| East Carolina University | Greenville | North Carolina | 27834 | — |
| Baylor Scott & White Research Institute | Dallas | Texas | 75246 | — |
| Baylor All Saints Medical Center at Fort Worth | Fort Worth | Texas | 76104 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04380961, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 21, 2022 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04380961 live on ClinicalTrials.gov.