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Completed Phase 1Phase 2 Interventional

Adenosine Receptor Antagonist Combination Therapy for Metastatic Castrate Resistant Prostate Cancer

ClinicalTrials.gov ID: NCT04381832

Public ClinicalTrials.gov record NCT04381832. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients With Metastatic Castrate Resistant Prostate Cancer

Study identification

NCT ID
NCT04381832
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
Arcus Biosciences, Inc.
Industry
Enrollment
173 participants

Conditions and interventions

Interventions

  • Etrumadenant Drug
  • Zimberelimab Drug
  • Quemliclustat Drug
  • Enzalutamide Drug
  • Docetaxel Drug
  • SG Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Male
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 6, 2020
Primary completion
Aug 29, 2024
Completion
Aug 29, 2024
Last update posted
Jul 21, 2025

2020 – 2024

United States locations

U.S. sites
17
U.S. states
9
U.S. cities
17
Facility City State ZIP Site status
The Oncology Institute of Hope & Innovation Cerritos California 90703
The University of California, Los Angeles Encino California 91436
The University of California, Irvine Medical Center Orange California 92868
Florida Cancer Specialists South Sarasota Florida 34232
Florida Cancer Specialists North St. Petersburg Florida 33705
Florida Cancer Specialists Panhandle Tallahassee Florida 32308
Florida Cancer Specialists East West Palm Beach Florida 33401
Northwestern University Feinberg School of Medicine Chicago Illinois 60611
Affinity Health Hope & Healing Cancer Services Hinsdale Illinois 60521
Johns Hopkins University Baltimore Maryland 21287
New York University, Langone Health New York New York 01006
Wilmot Cancer Institute Oncology, University of Rochester Rochester New York 14642
Cleveland Clinic Cleveland Ohio 44195
Tennessee Oncology - Chattanooga Chattanooga Tennessee 37404
Tennessee Oncology - Nashville Nashville Tennessee 37203
MD Anderson Cancer Center Houston Texas 77030
Medical Oncology Associates, PS (dba Summit Cancer Centers) Spokane Washington 99208

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04381832, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 21, 2025 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04381832 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →