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Completed Phase 2 Interventional Results available

UV1 Vaccination Plus Nivolumab and Ipilimumab in Treatment of Melanoma

ClinicalTrials.gov ID: NCT04382664

Public ClinicalTrials.gov record NCT04382664. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 11:51 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Efficacy and Safety of UV1 Vaccination in Combination With Nivolumab and Ipilimumab as First Line Treatment of Patients With Unresectable or Metastatic Melanoma (INITIUM Study)

Study identification

NCT ID
NCT04382664
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ultimovacs ASA
Industry
Enrollment
156 participants

Conditions and interventions

Interventions

  • Ipilimumab Biological
  • Nivolumab Biological
  • Sargramostim Biological
  • UV1 Biological

Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 26, 2020
Primary completion
Jan 10, 2024
Completion
Apr 9, 2024
Last update posted
Jan 13, 2025

2020 – 2024

United States locations

U.S. sites
20
U.S. states
11
U.S. cities
19
Facility City State ZIP Site status
Mayo Clinic Hospital Phoenix Arizona 85016-4880
Highlands Oncology Group Fayetteville Arkansas 72703
University of California Irvine Health Orange California 92868
California Cancer Associates for Research & Excellence (CCARE San Marcos California 92083
Ridley-Tree Cancer Center Santa Barbara California 93105
Saint John's Health Center - John Wayne Cancer Institute (JWCI) Santa Monica California 90404
University of Colorado Hospital - Anschutz Cancer Pavilion Aurora Colorado 80045
Holy Cross Medical Group Fort Lauderdale Florida 33308
Sylvester Comprehensive Cancer Center Miami Florida 33136-1002
Ocala Oncology Center Ocala Florida 34474
Rush University Medical Center - Rush University Cancer Center Chicago Illinois 60612-3841
NorthShore University Research Institute Evanston Illinois 60201-1718
Oncology Specialists, S.C. Park Ridge Illinois 60068
Norton Cancer Institute Louisville Kentucky 40241
Nebraska Cancer Specialists- Midwest Cancer Center Papillion Nebraska 68046-5706
Icahn School of Medicine at Mount Sinai New York New York 10029
State University of New York (SUNY) Upstate Medical University New York New York 13210
University of Rochester Rochester New York 14642-0001
NorthShore University HealthSystem Greenville South Carolina 29607
Texas Oncology - Baylor Charles A. Sammons Cancer Center Dallas Texas 75246-2092

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04382664, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 13, 2025 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04382664 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →