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Completed Phase 2 Interventional

Open-label Study Investigating of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

ClinicalTrials.gov ID: NCT04388475

Public ClinicalTrials.gov record NCT04388475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 12:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II Open-label Study Investigating the Efficacy, Safety and Pharmacokinetic Properties of OKN-007 Combined With Temozolomide in Patients With Recurrent Glioblastoma

Study identification

NCT ID
NCT04388475
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Oblato, Inc.
Industry
Enrollment
57 participants

Conditions and interventions

Interventions

  • OKN-007 Drug
  • Temozolomide (TMZ) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 11, 2020
Primary completion
May 7, 2024
Completion
Mar 4, 2025
Last update posted
Aug 11, 2025

2020 – 2025

United States locations

U.S. sites
13
U.S. states
13
U.S. cities
13
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294
St. Joseph's Hospital and Medical Center Phoenix Arizona 85013
Providence Saint John's Health Center - John Wayne Cancer Institute Santa Monica California 90404
Swedish Medical Center Englewood Colorado 80113
AdventHealth Orlando Orlando Florida 32804
University of Iowa Iowa City Iowa 52242
Norton Healthcare Louisville Kentucky 40241
Henry Ford Health System Detroit Michigan 48202
Wake Forest Baptist Comprehensive Cancer Center Winston-Salem North Carolina 27157
The University of Toledo Toledo Ohio 43606
The University of Oklahoma Oklahoma City Oklahoma 73117
Lifespan Office of Research Providence Rhode Island 02903
St. Joseph Hospital of Orange Seattle Washington 35143

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04388475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 11, 2025 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04388475 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →