ClinicalTrials.gov record
CHAMPION-AF Clinical Trial
ClinicalTrials.gov ID: NCT04394546
Public ClinicalTrials.gov record NCT04394546. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
WATCHMAN FLX Versus NOAC for Embolic ProtectION in in the Management of Patients With Non-Valvular Atrial Fibrillation
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to determine if left atrial appendage closure (LAAC) with the WATCHMAN FLX device is a reasonable alternative to non-vitamin K oral anticoagulants in patients with non-valvular atrial fibrillation.
Study identification
- NCT ID
- NCT04394546
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 3,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 15, 2020 (Actual)
- Primary completion
- Dec 2027 (Estimated)
- Completion
- Dec 2027 (Estimated)
- Last update posted
- Oct 14, 2026
2020 – 2027
United States locations
- U.S. sites
- 95
- U.S. states
- 36
- U.S. cities
- 86
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Grandview Medical Center | Birmingham | Alabama | 35243 | — |
| University of Alabama at Birmingham | Birmingham | Alabama | 35294-6830 | — |
| Arizona Arrhythmia Research Center | Phoenix | Arizona | 85016 | — |
| Phoenix Cardiovascular Research Group | Phoenix | Arizona | 85018 | — |
| Scottsdale Healthcare - Shea | Scottsdale | Arizona | 85258 | — |
| PIMA Heart and Vascular | Tucson | Arizona | 85741 | — |
| Arrythmia Research Group | Jonesboro | Arkansas | 72401 | — |
| Sharp Chula Vista Medical Center | Chula Vista | California | 91911 | — |
| Marin General Hospital | Greenbrae | California | 94904 | — |
| Scripps Memorial Hospital | La Jolla | California | 92037 | — |
| Los Robles Hospital and Medical Center | Los Angeles | California | 91360 | — |
| El Camino Hospital | Mountain View | California | 94040 | — |
| Eisenhower Medical Center | Rancho Mirage | California | 92270 | — |
| Mercy General Hospital | Sacramento | California | 95819 | — |
| Santa Barbara Cottage Hospital | Santa Barbara | California | 93105 | — |
| St. John's Health Center | Santa Monica | California | 90404 | — |
| Colorado Springs Cardiologist, P.C. | Colorado Springs | Colorado | 80923 | — |
| Yale University School of Medicine | New Haven | Connecticut | 06473 | — |
| Christiana Hospital | Newark | Delaware | 19718 | — |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Manatee Memorial Hospital | Bradenton | Florida | 34205 | — |
| Bay Area Cardiology Associates, P.A. | Brandon | Florida | 33511 | — |
| Broward General Medical Center | Fort Lauderdale | Florida | 33316 | — |
| St. Vincent's Medical Center | Jacksonville | Florida | 32204 | — |
| Lakeland Regional Medical Center | Lakeland | Florida | 33805 | — |
| Baptist Hospital of Miami | Miami | Florida | 33176 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Tallahassee Memorial Hospital | Tallahassee | Florida | 32308 | — |
| Piedmont Hospital | Atlanta | Georgia | 30309 | — |
| Emory University Hospital | Atlanta | Georgia | 30322 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| St. John's Hospital | Springfield | Illinois | 62701 | — |
| Franciscan Health Indianapolis | Indianapolis | Indiana | 46237 | — |
| Community Hospital | Munster | Indiana | 46321 | — |
| Mercy Hospital Medical Center | Des Moines | Iowa | 50314 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| University of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Norton Hospital | Louisville | Kentucky | 40202 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Lahey Clinic Hospital | Burlington | Massachusetts | 01805 | — |
| Charlton Memorial | Fall River | Massachusetts | 02720 | — |
| University of Massachusetts Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Sparrow Health System - Sparrow Hospital | Lansing | Michigan | 48912 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Mercy Hospital | Coon Rapids | Minnesota | 55433 | — |
| Mayo Clinic Foundation | Rochester | Minnesota | 55905 | — |
| Centracare Heart and Vascular Center | Saint Cloud | Minnesota | 56303 | — |
| HealthEast St. Joseph's Hospital | Saint Paul | Minnesota | 55102 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| St. Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Billings Clinic | Billings | Montana | 59101 | — |
| Bergan Cardiology | Omaha | Nebraska | 68124 | — |
| The Nebraska Medical Center | Omaha | Nebraska | 68198 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Catholic Medical Center | Manchester | New Hampshire | 03102 | — |
| Englewood Hospital and Medical Center | Englewood | New Jersey | 07631 | — |
| Kaleida Health | Buffalo | New York | 14203 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| Columbia University Medical Center | New York | New York | 10032 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| Novant Health Presbyterian Medical Center | Charlotte | North Carolina | 28204 | — |
| University Hospitals of Cleveland | Cleveland | Ohio | 44106 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| OhioHealth Research and Innovation Institute-Riverside Methodist Hospital | Columbus | Ohio | 43214 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| The Toledo Hospital | Toledo | Ohio | 43606 | — |
| Legacy Emanuel Hospital & Health Center | Portland | Oregon | 97227 | — |
| Pinnacle Health at Harrisburg Hospital | Harrisburg | Pennsylvania | 17101 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| York Hospital | York | Pennsylvania | 17403 | — |
| Trident Medical Center | Charleston | South Carolina | 29406 | — |
| Medical University of South Carolina | Columbia | South Carolina | 29204 | — |
| Lexington Medical Center | West Columbia | South Carolina | 29169 | — |
| Erlanger Medical Center | Chattanooga | Tennessee | 37403 | — |
| Methodist Le Bonheur Healthcare | Germantown | Tennessee | 38138 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232-7235 | — |
| Texas Cardiac Arrhythmia Research | Austin | Texas | 78705 | — |
| Heart Hospital of Austin | Austin | Texas | 78756 | — |
| Memorial Hermann Memorial City Medical Center | Houston | Texas | 77024 | — |
| The Heart Hospital Baylor Plano | Plano | Texas | 75093 | — |
| Methodist Texsan Hospital | San Antonio | Texas | 78201-2009 | — |
| Christus Trinity Mother Frances Health System | Tyler | Texas | 75701 | — |
| Inova Fairfax Hospital | Falls Church | Virginia | 22042 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23219 | — |
| Providence Regional Medical Center Everett | Everett | Washington | 98201 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| CHI Franciscan Health System | Tacoma | Washington | 98405 | — |
| PeaceHealth Southwest Medical | Vancouver | Washington | 98668 | — |
| Monongalia General Hospital | Morgantown | West Virginia | 26505 | — |
| Aurora St. Luke's Medical Center | Milwaukee | Wisconsin | 52315 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04394546, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04394546 live on ClinicalTrials.gov.