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Terminated Phase 2 Interventional Results available

A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection

ClinicalTrials.gov ID: NCT04398134

Public ClinicalTrials.gov record NCT04398134. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 11:09 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Multicenter, Single-Blind, Placebo-Controlled, Multiple Cohort Study Evaluating ABI-H2158-Containing Regimens in Chronic Hepatitis B Infection

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This Phase 2a study will assess the safety, antiviral activity, and pharmacokinetics (PK) of ABI-H2158 administered once daily for up to 72 weeks in combination with entecavir (ETV) in participants with chronic hepatitis B virus (HBV) infection.

Study identification

NCT ID
NCT04398134
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Assembly Biosciences
Industry
Enrollment
88 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 27, 2020
Primary completion
Oct 13, 2021
Completion
Dec 27, 2021
Last update posted
Sep 14, 2022

2020 – 2021

United States locations

U.S. sites
13
U.S. states
7
U.S. cities
13
Facility City State ZIP Site status
Coalition of Inclusive Medicine Los Angeles California 90020
California Liver Research Institute Pasadena California 91105
Stanford University Medical Center Redwood City California 94063
Research and Education Inc. San Diego California 92105
Quest Clinical Research San Francisco California 94115
University of Miami/Schiff Center for Liver Diseases Miami Florida 33136
Johns Hopkins University Baltimore Maryland 21287
New Discovery, LLC Flushing New York 11355
Northwell Health Center for Liver Disease Manhasset New York 11030
NYU Langone Health New York New York 10016
Thomas Jefferson University Philadelphia Pennsylvania 19107
American Research Corporation at the Texas Liver Institute San Antonio Texas 78215
University of Washington Seattle Washington 98104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04398134, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 14, 2022 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04398134 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →