Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Completed Phase 1 Interventional

A Study of ION251 Administered to Patients With Relapsed/Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT04398485

Public ClinicalTrials.gov record NCT04398485. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 7, 2026, 10:16 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 Study of ION251 Administered by Intravenous Infusion to Patients With Relapsed/Refractory Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to determine the maximum-tolerated dose (MTD) and recommended Phase 2 dose (RP2D) of ION251 in patients with relapsed/refractory multiple myeloma.

Study identification

NCT ID
NCT04398485
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Ionis Pharmaceuticals, Inc.
Industry
Enrollment
23 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 20, 2021 (Actual)
Primary completion
Sep 30, 2024 (Actual)
Completion
Sep 30, 2024 (Actual)
Last update posted
Oct 31, 2024

2021 – 2024

United States locations

U.S. sites
6
U.S. states
4
U.S. cities
5
Facility City State ZIP Site status
University of California San Diego Moores Cancer Center La Jolla California 92093 —
Cedars-Sinai Medical Center Los Angeles California 90048 —
UCLA Rrmc Los Angeles California 90095 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 —
Washington University School of Medicine in Saint Louis St Louis Missouri 63130 —
Levine Cancer Institute Charlotte North Carolina 28204 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04398485, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 31, 2024 · Synced Nov 7, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04398485 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →