Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle Glaucoma
Public ClinicalTrials.gov record NCT04405245. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 2 Multi-Center, Double-Masked, Randomized, 28-Day Study to Assess the Efficacy, Safety and Tolerability of Single or Twice Daily Doses of AKB-9778 Ophthalmic Solution as an Adjunct to Latanoprost in Patients With Ocular Hypertension (OHT) or Open Angle Glaucoma (OAG)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a phase 2, double masked, randomized, multi-center, parallel-group, 28-day study assessing the safety, tolerability and ocular hypotensive efficacy of AKB-9778 Ophthalmic Solution 4.0% administered once (AM) or twice (AM \& PM) daily when used as an adjunctive therapy to latanoprost ophthalmic solution 0.005% once daily (PM) in subjects with elevated IOP due to OAG or OHT.
Study identification
- NCT ID
- NCT04405245
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 194 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 6, 2020 (Actual)
- Primary completion
- Nov 5, 2020 (Actual)
- Completion
- Nov 5, 2020 (Actual)
- Last update posted
- May 25, 2023
2020
United States locations
- U.S. sites
- 21
- U.S. states
- 12
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| United Medical Research Institute | Inglewood | California | 90301 | — |
| North Valley Eye Medical Group | Mission Hills | California | 91345 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| North Bay Eye Associates | Petaluma | California | 94954 | — |
| Shettle Eye Research | Largo | Florida | 33773 | — |
| Clayton Eye Clinical Research, LLC | Morrow | Georgia | 30260 | — |
| Coastal Research Associates | Roswell | Georgia | 30076 | — |
| Kannarr Eye Care | Pittsburg | Kansas | 66762 | — |
| Heart of America Eye Care, P.A. | Shawnee Mission | Kansas | 66204 | — |
| Tekwani Vision Center | St Louis | Missouri | 63128 | — |
| North Valley Eye Medical Group | Rochester | New York | 14618 | — |
| Charlotte Eye, Ear, Nose & Throat Assoc. (CEENTA) | Charlotte | North Carolina | 28210 | — |
| James D. Branch, MD Ophthalmology | Winston-Salem | North Carolina | 27101 | — |
| Apex Eye | Cincinnati | Ohio | 45242 | — |
| Abrams Eye Center | Cleveland | Ohio | 44115 | — |
| Mark J. Weiss, MD, Inc. | Tulsa | Oklahoma | 74104 | — |
| Scott & Christie and Assoc | Cranberry Township | Pennsylvania | 16066 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Total Eye Care | Memphis | Tennessee | 38119 | — |
| Advancing Vision Research | Nashville | Tennessee | 37205 | — |
| Texan Eye / Keystone Research | Austin | Texas | 78731 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04405245, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 25, 2023 · Synced Oct 25, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04405245 live on ClinicalTrials.gov.