Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Public ClinicalTrials.gov record NCT04408755. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 (Deudextromethorphan Hydrobromide [d6-DM]/Quinidine Sulfate [Q]) for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study was conducted to evaluate the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide \[d6-DM\]/quinidine sulfate \[Q\]) compared to placebo for the treatment of agitation in participants with dementia of the Alzheimer's type.
Study identification
- NCT ID
- NCT04408755
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 184 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2020
- Primary completion
- Jun 26, 2024
- Completion
- Jun 26, 2024
- Last update posted
- May 29, 2025
2020 – 2024
United States locations
- U.S. sites
- 45
- U.S. states
- 14
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Site #840-081 | Fort Smith | Arkansas | 72901 | — |
| Clinical Research Site #840-035 | La Jolla | California | 92093 | — |
| Clinical Research Site #840-084 | Los Angeles | California | 70072 | — |
| Clinical Research Site #840-050 | Oceanside | California | 92056 | — |
| Clinical Research Site #840-064 | Pasadena | California | 91105 | — |
| Clinical Research Site #840-098 | Santa Ana | California | 92705 | — |
| Clinical Research Site #840-090 | Basalt | Colorado | 81621 | — |
| Clinical Research Site #840-009 | Atlantis | Florida | 33462 | — |
| Clinical Research Site #840-056 | Brandon | Florida | 33511 | — |
| Clinical Research Site #840-020 | Coral Gables | Florida | 33134 | — |
| Clinical Research Site #840-059 | Doral | Florida | 33166 | — |
| Clinical Research Site #840-131 | Hialeah | Florida | 33012 | — |
| Clinical Research Site #840-039 | Jacksonville | Florida | 32256 | — |
| Clinical Research Site #840-012 | Kissimmee | Florida | 34744 | — |
| Clinical Research Site #840-069 | Maitland | Florida | 32751 | — |
| Clinical Research Site #840-083 | Maitland | Florida | 32751 | — |
| Clinical Research Site #840-118 | Miami | Florida | 33032 | — |
| Clinical Research Site #840-004 | Miami | Florida | 33126 | — |
| Clinical Research Site #840-125 | Miami | Florida | 33126 | — |
| Clinical Research Site #840-104 | Miami | Florida | 33144 | — |
| Clinical Research Site #840-133 | Miami | Florida | 33165 | — |
| Clinical Research Site #840-042 | Miami | Florida | 33175 | — |
| Clinical Research Site #840-003 | Miami | Florida | 33467 | — |
| Clinical Research Site #840-036 | Orlando | Florida | 32819 | — |
| Clinical Research Site 840-111 | Pembroke Pines | Florida | 33024 | — |
| Clinical Research Site #840-096 | Pensacola | Florida | 32503 | — |
| Clinical Research Site | Pompano Beach | Florida | 33064 | — |
| Clinical Research Site #840-079 | Tampa | Florida | 33614 | — |
| Clinical Research Site #840-112 | Tampa | Florida | 33615 | — |
| Clinical Research Site #840-046 | Tampa | Florida | 33634 | — |
| Clinical Research Site #840-107 | West Palm Beach | Florida | 33407 | — |
| Clinical Research Site #840-049 | Glen Burnie | Maryland | 21061 | — |
| Clinical Research Site #840-093 | Rochester Hills | Michigan | 48307 | — |
| Clinical Research Site #840-015 | Hattiesburg | Mississippi | 39401 | — |
| Clinical Research Site #840-029 | West Long Branch | New Jersey | 07764 | — |
| Clinical Research Site #840-072 | New Windsor | New York | 12553 | — |
| Clinical Research Site #840-097 | The Bronx | New York | 10466 | — |
| Clinical Research Site #840-095 | Monroe | North Carolina | 28112 | — |
| Clinical Research Site #840-060 | Canton | Ohio | 44718 | — |
| Clinical Research Site #840-028 | Columbus | Ohio | 43210 | — |
| Clinical Research Site #840-061 | Edmond | Oklahoma | 73012 | — |
| Clinical Research Site #840-099 | Tulsa | Oklahoma | 74136 | — |
| Clinical Research Site #840-115 | McKinney | Texas | 75069 | — |
| Clinical Research Site | The Woodlands | Texas | 77381 | — |
| Clinical Research Site #840-025 | Richmond | Virginia | 23236 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04408755, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 29, 2025 · Synced Sep 1, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04408755 live on ClinicalTrials.gov.