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Completed Phase 2Phase 3 Interventional Results available

Long-term Safety Study of BHV-3500 (Zavegepant*) for the Acute Treatment of Migraine

ClinicalTrials.gov ID: NCT04408794

Public ClinicalTrials.gov record NCT04408794. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 9:01 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2/3 Open-label, Long-Term, Safety Trial of BHV3500 (Zavegepant*) Intranasal (IN) for the Acute Treatment of Migraine

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the long-term safety of BHV-3500/vazegepant intranasal in the acute treatment of migraine. \* BHV-3500, formerly "vazegepant", is now referred to as "zavegepant" (za ve' je pant). The World Health Organization (WHO) International Nonproprietary Names (INN) Expert Committee revised the name to "zavegepant" which was accepted by the United States Adopted Names (USAN ) Council for use in the U.S. and is pending formal adoption by the INN for international use.

Study identification

NCT ID
NCT04408794
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Pfizer
Industry
Enrollment
974 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 28, 2020
Primary completion
Dec 8, 2021
Completion
Dec 22, 2021
Last update posted
May 17, 2023

2020 – 2021

United States locations

U.S. sites
67
U.S. states
29
U.S. cities
65
Facility City State ZIP Site status
Medical Affiliated Research Center Huntsville Alabama 35801
Coastal Clinical Research, LLC, An AMR Co. Mobile Alabama 36608
Tucson Neuroscience Research Tucson Arizona 85710
Baptist Health Center for Clinical Research Little Rock Arkansas 72205
Pharmacology Research Institute Encino California 91316
eStudySite La Mesa California 91942
Synergy San Diego Lemon Grove California 91945
Collaborative Neuroscience Network, LLC Long Beach California 90806
Pharmacology Research Institute Los Alamitos California 90720
Wr-Pri, Llc Newport Beach California 92660
Artemis Institute for Clinical Research San Diego California 92103
Artemis Institute for Clinical Research San Marcos California 92078
California Medical Clinic for Headache Santa Monica California 90404
California Neuroscience Research Medical Group, Inc. Sherman Oaks California 91403
CT Clinical Research Cromwell Connecticut 06416
Ki Health Partners, LLC dba New England Institute for Clinical Research Stamford Connecticut 06905
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Multi-Specialty Research Associates, Inc. Lake City Florida 32055
Clinical Neuroscience Solutions, Inc. Orlando Florida 32801
Clinical Neuroscience Solutions, Inc. Orlando Florida 32819
Ormond Medical Arts Pharmaceutical Research Center Ormond Beach Florida 32174
Meridien Research Tampa Florida 33634
iResearch Atlanta, LLC Decatur Georgia 30030
Meridian Clinical Research, LLC Savannah Georgia 31406
Northwest Clinical Trials Inc. Boise Idaho 83704
Community Hospital of Anderson and Madison County Inc Anderson Indiana 46011
Fort Wayne Neurological Center Fort Wayne Indiana 46804
Collective Medical Research Prairie Village Kansas 66208
Crescent City Headache and Neurology Center Chalmette Louisiana 70043
Boston Clinical Trials Boston Massachusetts 02131
Community Clinical Research Network Marlborough Massachusetts 01752
Boston Neuro Research Center South Dartmouth Massachusetts 02747
Medvadis Research Corporation Waltham Massachusetts 02451
Michigan Headache and Neurological Institute Ann Arbor Michigan 48104
Clinical Research Institute, Inc. Minneapolis Minnesota 55402
StudyMetrix Research City of Saint Peters Missouri 63303
Clinvest Research LLC Springfield Missouri 65810
Sundance Clinical Research, LLC St Louis Missouri 63141
Dartmouth-Hitchcock Heater Road Lebanon New Hampshire 03766
Albuquerque Clinical Trials, Inc. Albuquerque New Mexico 87102
Regional Clinical Research Endwell New York 13760
Fieve Clinical Research, Inc New York New York 10017
Rochester Clinical Research, Inc. Rochester New York 14609
Montefiore Medical Center: Headache Center The Bronx New York 10461
Headache Wellness Center Greensboro North Carolina 27405
PharmQuest LLC Greensboro North Carolina 27408
Wilmington Health, PLLC Wilmington North Carolina 28401
OK Clinical Research LLC Edmond Oklahoma 73034
Tekton Research, Inc. Yukon Oklahoma 73099
Summit Research Network Portland Oregon 97210
Clinical Research of Philadelphia, LLC Philadelphia Pennsylvania 19114
Preferred Primary Care Physicians, Inc. Pittsburgh Pennsylvania 15236
Preferred Primary Care Physicians, Inc. Union Pennsylvania 15401
Coastal Carolina Research Center Mt. Pleasant South Carolina 29464
Volunteer Research Group Knoxville Tennessee 37920
Clinical Neuroscience Solutions, Inc. Memphis Tennessee 38119
FutureSearch Trials of Neurology Austin Texas 78731
FutureSearch Trials of Dallas, LP Dallas Texas 75231
Red Star Research LLC Lake Jackson Texas 77566
DM Clinical Research Tomball Texas 77375
Wasatch Clinical Research, LLC Salt Lake City Utah 84107
J. Lewis Research, Inc. / Jordan River Family Medicine South Jordan Utah 84095
Charlottesville Medical Research Center, LLC Charlottesville Virginia 22911
Tidewater Integrated Medical Research Virginia Beach Virginia 23454
Northwest Clinical Research Center Bellevue Washington 98007
Seattle Women's: Health, Research, Gynecology Seattle Washington 98105
Clinical Investigation Specialist, Inc. Kenosha Wisconsin 53144

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04408794, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 17, 2023 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04408794 live on ClinicalTrials.gov.

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