A Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Participants With Severe COVID-19 Pneumonia
Public ClinicalTrials.gov record NCT04409262. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Randomized, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of Remdesivir Plus Tocilizumab Compared With Remdesivir Plus Placebo in Hospitalized Patients With Severe COVID-19 Pneumonia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of combination therapy with remdesivir plus tocilizumab compared with remdesivir plus placebo in hospitalized patients with COVID-19 pneumonia.
Study identification
- NCT ID
- NCT04409262
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 649 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 16, 2020 (Actual)
- Primary completion
- Feb 1, 2021 (Actual)
- Completion
- Mar 8, 2021 (Actual)
- Last update posted
- Feb 14, 2022
2020 – 2021
United States locations
- U.S. sites
- 38
- U.S. states
- 23
- U.S. cities
- 36
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Valleywise Health Medical Center | Phoenix | Arizona | 85008 | — |
| eStudySite - Chula Vista - PPDS | Chula Vista | California | 91911 | — |
| Hoag Hospital Irvine | Irvine | California | 92612 | — |
| Providence St Johns Health Center | Santa Monica | California | 90404 | — |
| Yale University School of Medicine; HIV Clinical Trials Program | New Haven | Connecticut | 06501 | — |
| Medstar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Holy Cross Hospital Inc | Fort Lauderdale | Florida | 33308 | — |
| Larkin Community Hospital Palm Springs Campus (Hialeah) | Hialeah | Florida | 33012 | — |
| University of Miami Miller School of Medicine; Clinical Reseach Building | Miami | Florida | 33136 | — |
| Larkin Community Hospital | South Miami | Florida | 33143 | — |
| St Luke's Health System; Rheumatology Research | Boise | Idaho | 83702 | — |
| Advocate Christ Medical Center | Oak Lawn | Illinois | 60453 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| University of Maryland | Baltimore | Maryland | 21201 | — |
| Boston Medical Center | Boston | Massachusetts | 02118-2393 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| Henry Ford Medical Center | Novi | Michigan | 48322 | — |
| St. Michael'S Medical Center | Newark | New Jersey | 07102 | — |
| San Juan Oncology Associates | Farmington | New Mexico | 87401 | — |
| Wyckoff Heights Medical Center | Staten Island | New York | 11237 | — |
| Novant Health Clinical Research | Charlotte | North Carolina | 28204 | — |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | — |
| Providence Saint Vincent's Medical Center | Portland | Oregon | 97225 | — |
| Lehigh Valley Hospital | Allentown | Pennsylvania | 18103 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| The Liver Institute at Methodist Dallas | Arlington | Texas | 76012 | — |
| Baylor Scott and White Medical Center - College Station | College Station | Texas | 77845 | — |
| Baylor University Medical Center | Dallas | Texas | 75231 | — |
| Baylor St. Luke's Medical Center | Houston | Texas | 77030 | — |
| Ben Taub General Hospital - HCHD | Houston | Texas | 77030 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Baylor Scott & White Medical Center - Irving | Irving | Texas | 75061 | — |
| Baylor Scott & White Hospital - Plano | Plano | Texas | 75093 | — |
| Baylor Scott & White Health | Temple | Texas | 76502 | — |
| Intermountain LDS Hospital | Salt Lake City | Utah | 84143 | — |
| The Providence Regional Medical Center Everett | Everett | Washington | 98201 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04409262, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 14, 2022 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04409262 live on ClinicalTrials.gov.