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Completed Phase 1 Interventional Results available

A Study of LY3819253 (LY-CoV555) in Participants Hospitalized for COVID-19

ClinicalTrials.gov ID: NCT04411628

Public ClinicalTrials.gov record NCT04411628. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Placebo-Controlled, Double-Blind, Sponsor Unblinded, Single Ascending Dose, Phase 1 First in Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous LY3819253 in Participants Hospitalized for COVID-19

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to test the safety and tolerability of LY3819253 when it is given by injection into a vein to participants hospitalized with COVID-19. Blood tests will be done to check how much LY3819253 is in the bloodstream and how long the body takes to eliminate it. Participation could last about 8 weeks and may include up to 15 visits in the hospital or the home.

Study identification

NCT ID
NCT04411628
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
26 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 27, 2020
Primary completion
Aug 25, 2020
Completion
Aug 25, 2020
Last update posted
Nov 11, 2021

2020

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
11
Facility City State ZIP Site status
Cedars Sinai Medical Center Los Angeles California 90048
Veterans Affairs Medical Center San Diego San Diego California 92161
Emory University Atlanta Georgia 30322
Massachusetts General Hospital Boston Massachusetts 02114
University of Massachusetts Medical Center Worcester Massachusetts 01655
University of Michigan Ann Arbor Michigan 48109
Quality Clinical Research, Inc. Omaha Nebraska 68114
Alexandria Center for Life - NYC/ NYCEDC New York New York 10016
University of North Carolina Chapel Hill North Carolina 27514
Unified Research Enterprise Brody School of Medicine at ECU Greenville North Carolina 27834
Temple Univ School of Med Philadelphia Pennsylvania 19140

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04411628, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 11, 2021 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04411628 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →