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Completed Phase 2 Interventional Results available

Study to Evaluate the Safety and Efficacy of ATYR1923 (Efzofitimod) In Participants With Severe Pneumonia Related to COVID-19

ClinicalTrials.gov ID: NCT04412668

Public ClinicalTrials.gov record NCT04412668. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 10:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of ATYR1923 In Adult Patients With Severe Pneumonia Related to SARS-CoV-2 Infection (COVID-19)

Study identification

NCT ID
NCT04412668
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
aTyr Pharma, Inc.
Industry
Enrollment
36 participants

Conditions and interventions

Interventions

  • Efzofitimod 1 mg/kg Drug
  • Efzofitimod 3 mg/kg Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 3, 2020
Primary completion
Oct 22, 2020
Completion
Oct 22, 2020
Last update posted
Aug 17, 2023

2020

United States locations

U.S. sites
8
U.S. states
8
U.S. cities
8
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294
aTyr Investigative Site Washington D.C. District of Columbia 20010
University of Miami Miami Florida 33125
University of Iowa Iowa City Iowa 52242
Anne Arundel Medical Center Annapolis Maryland 21401
aTyr Investigative Site Vineland New Jersey 08360
aTyr Investigative Site Toledo Ohio 43614
Inova Fairfax Medical Campus Falls Church Virginia 22042

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04412668, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 17, 2023 · Synced Jul 21, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04412668 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →