Vascular Endothelial Growth Factor-B (VEGF-B) Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease
Public ClinicalTrials.gov record NCT04419467. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Phase 2a, Double-blind, Randomized, Placebo-controlled, Proof of Concept Study of Vascular Endothelial Growth Factor (VEGF)-B Blockade With the Monoclonal Antibody CSL346 in Subjects With Diabetic Kidney Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This phase 2a, double-blind, randomized, placebo-controlled study will assess the efficacy, safety, tolerability, and pharmacokinetics (PK), of repeat doses of CSL346 in subjects with diabetic kidney disease (DKD) and albuminuria receiving standard of care treatment.
Study identification
- NCT ID
- NCT04419467
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 114 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 25 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 14, 2020 (Actual)
- Primary completion
- Oct 24, 2022 (Actual)
- Completion
- Oct 24, 2022 (Actual)
- Last update posted
- Dec 6, 2023
2020 – 2022
United States locations
- U.S. sites
- 22
- U.S. states
- 11
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| California Kidney Specialists (CKS) - Citrus Office | Covina | California | 91702 | — |
| Valley Research - Fresno | Fresno | California | 93720 | — |
| Torrance Clinical Research (TCR) - Lomita | Lomita | California | 90717 | — |
| Renal Medical Associate/NARI | Lynwood | California | 90260 | — |
| Amicis Research Center | Northridge | California | 91324 | — |
| California Medical Research Associates, Inc | Northridge | California | 91324 | — |
| Riverside Nephrology Group | Riverside | California | 92503 | — |
| West Orange Endocrinology | Ocoee | Florida | 34761 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| Renal and Transplant Associates | Springfield | Massachusetts | 01107 | — |
| University of Missouri Health System | Columbia | Missouri | 65212 | — |
| Palm Medical Group, LLC - Las Vegas | Las Vegas | Nevada | 89148 | — |
| Center for Thyroid & Parathyroid Disorders | Staten Island | New York | 10301 | — |
| Physicians East, P.A. - Endocrinology | Greenville | North Carolina | 27834 | — |
| Vanderbilt University School of Medicine | Nashville | Tennessee | 37232 | — |
| Juno Research, L.L.C. | Houston | Texas | 77040 | — |
| The Endocrine Center | Houston | Texas | 77079 | — |
| Renal Associates, P.A. - San Antonio | San Antonio | Texas | 78215 | — |
| Primary Care Providers of Texas | San Antonio | Texas | 78224 | — |
| Diabetes and Metabolism Specialists (DMS) - San Antonio | San Antonio | Texas | 78231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04419467, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 6, 2023 · Synced Nov 7, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04419467 live on ClinicalTrials.gov.