A Study of DF6002 Alone and in Combination With Nivolumab
Public ClinicalTrials.gov record NCT04423029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/1b, First-In-Human, Multi-Part, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of DF6002 as a Monotherapy and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion in Selected Indications
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety, tolerability, drug-levels, drug-effects and preliminary anti-tumor activity of DF6002 alone and in combination with Nivolumab in participants with advanced solid tumors.
Study identification
- NCT ID
- NCT04423029
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 170 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 13, 2020 (Actual)
- Primary completion
- Nov 26, 2025 (Actual)
- Completion
- Nov 26, 2025 (Actual)
- Last update posted
- Mar 18, 2026
2020 – 2025
United States locations
- U.S. sites
- 21
- U.S. states
- 19
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California Irvine | Orange | California | 92868 | — |
| SCRI - HealthOne Denver | Denver | Colorado | 80218 | — |
| Yale School of Medicine | New Haven | Connecticut | 06520 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Augusta University Georgia Cancer Center | Augusta | Georgia | 30912-0003 | — |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | — |
| Local Institution | Boston | Massachusetts | 02215 | — |
| Barbara Ann Karmanos Cancer Institute | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| HealthPartners Cancer Center at Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Atlantic Health System | Morristown | New Jersey | 07960 | — |
| Roswell Park Comprehensive Cancer Center | Buffalo | New York | 14263 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Stephenson Cancer Center | Oklahoma City | Oklahoma | 73104 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| SCRI - Tennessee Oncology - Saint Thomas West Clinic | Nashville | Tennessee | 37205 | — |
| University of Texas MD Anderson Cancer Center | Houston | Texas | 77030 | — |
| Huntsman Cancer Institute and Hospital | Salt Lake City | Utah | 84112 | — |
| USOR - Virginia Cancer Specialists - Fairfax Office | Fairfax | Virginia | 22031 | — |
| Froedtert Hospital | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04423029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 18, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04423029 live on ClinicalTrials.gov.