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Completed Phase 1 Interventional

A Study of DF6002 Alone and in Combination With Nivolumab

ClinicalTrials.gov ID: NCT04423029

Public ClinicalTrials.gov record NCT04423029. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 1:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/1b, First-In-Human, Multi-Part, Open-Label, Multiple-Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological, and Clinical Activity of DF6002 as a Monotherapy and in Combination With Nivolumab in Patients With Locally Advanced or Metastatic Solid Tumors, and Expansion in Selected Indications

Study identification

NCT ID
NCT04423029
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Dragonfly Therapeutics
Industry
Enrollment
170 participants

Conditions and interventions

Conditions

Interventions

  • DF6002 Drug
  • Nivolumab Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 12, 2020
Primary completion
Nov 25, 2025
Completion
Nov 25, 2025
Last update posted
Mar 17, 2026

2020 – 2025

United States locations

U.S. sites
21
U.S. states
19
U.S. cities
20
Facility City State ZIP Site status
University of California Irvine Orange California 92868
SCRI - HealthOne Denver Denver Colorado 80218
Yale School of Medicine New Haven Connecticut 06520
University of Miami Miami Florida 33136
Augusta University Georgia Cancer Center Augusta Georgia 30912-0003
University of Iowa Hospitals and Clinics Iowa City Iowa 52242
Local Institution Boston Massachusetts 02215
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201
Henry Ford Hospital Detroit Michigan 48202
HealthPartners Cancer Center at Regions Hospital Saint Paul Minnesota 55101
Atlantic Health System Morristown New Jersey 07960
Roswell Park Comprehensive Cancer Center Buffalo New York 14263
Montefiore Medical Center The Bronx New York 10467
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Stephenson Cancer Center Oklahoma City Oklahoma 73104
Rhode Island Hospital Providence Rhode Island 02903
SCRI - Tennessee Oncology - Saint Thomas West Clinic Nashville Tennessee 37205
University of Texas MD Anderson Cancer Center Houston Texas 77030
Huntsman Cancer Institute and Hospital Salt Lake City Utah 84112
USOR - Virginia Cancer Specialists - Fairfax Office Fairfax Virginia 22031
Froedtert Hospital Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04423029, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 17, 2026 · Synced Jul 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04423029 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →