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Completed Phase 2 Interventional Results available

A Study of Oral Upadacitinib Tablet Compared to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa to Assess Change in Disease Symptoms

ClinicalTrials.gov ID: NCT04430855

Public ClinicalTrials.gov record NCT04430855. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 26, 2026, 2:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Multicenter, Randomized, Placebo-Controlled, Double-Blind Study to Evaluate Upadacitinib in Adult Subjects With Moderate to Severe Hidradenitis Suppurativa

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Hidradenitis suppurativa (HS) is an inflammatory skin disease that causes painful lesions in the axilla (underarm), inguinal (groin) and anogenital (anal and genital) regions. This study will evaluate how well upadacitinib compared to placebo (no medicine) works to treat hidradenitis suppurativa in adult participants with moderate to severe disease. The study will assess change in disease signs and symptoms.

Study identification

NCT ID
NCT04430855
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AbbVie
Industry
Enrollment
68 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 14, 2020 (Actual)
Primary completion
Apr 22, 2021 (Actual)
Completion
Jan 25, 2022 (Actual)
Last update posted
Feb 6, 2023

2020 – 2022

United States locations

U.S. sites
18
U.S. states
16
U.S. cities
18
Facility City State ZIP Site status
Medical Dermatology Specialist /ID# 221084 Phoenix Arizona 85006-2722 —
University of Arkansas for Medical Sciences /ID# 218404 Little Rock Arkansas 72205 —
Medderm Associates /ID# 218317 San Diego California 92103 —
Skin Care Research - Boca Raton /ID# 218809 Boca Raton Florida 33486-2269 —
Lakes Research, LLC /ID# 218854 Miami Florida 33014 —
ForCare Clinical Research /ID# 218013 Tampa Florida 33613-1244 —
Northshore University Health System Dermatology Clinical Trials Unit /ID# 218319 Skokie Illinois 60077 —
Dawes Fretzin, LLC /ID# 218310 Indianapolis Indiana 46256 —
Beth Israel Deaconess Medical Center /ID# 218306 Boston Massachusetts 02215-5400 —
Washington University-School of Medicine /ID# 218331 St Louis Missouri 63110 —
Psoriasis Treatment Center of Central New Jersey /ID# 218330 East Windsor New Jersey 08520 —
Duke Cancer Center /ID# 218526 Durham North Carolina 27710-3000 —
University Hospitals Case Medical Center /ID# 218326 Cleveland Ohio 44106 —
Southside Dermatology /ID# 218321 Tulsa Oklahoma 74132 —
University of Pittsburgh MC /ID# 218329 Pittsburgh Pennsylvania 15260 —
Medical University of South Carolina /ID# 218318 Charleston South Carolina 29425 —
Duplicate_Center for Clinical Studies /ID# 218307 Houston Texas 77004 —
Dermatology Specialists of Spokane /ID# 218760 Spokane Washington 99202 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04430855, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 6, 2023 · Synced Oct 26, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04430855 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →