ClinicalTrials.gov record
A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema
ClinicalTrials.gov ID: NCT04432831
Public ClinicalTrials.gov record NCT04432831. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Patients With Diabetic Macular Edema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter long-term extension study designed to evaluate the long-term safety and tolerability of faricimab administered by intravitreal (IVT) injection at a personalized treatment interval (PTI) to participants who enrolled in and completed one of the two Phase III studies, GR40349 (NCT03622580) or GR40398 (NCT03622593), also referred to as the parent studies.
Study identification
- NCT ID
- NCT04432831
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,479 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 4, 2020
- Primary completion
- Oct 10, 2023
- Completion
- Oct 10, 2023
- Last update posted
- Feb 8, 2026
2020 – 2023
United States locations
- U.S. sites
- 119
- U.S. states
- 35
- U.S. cities
- 108
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barnet Dulaney Perkins Eye Center | Mesa | Arizona | 85206 | — |
| Retinal Research Institute, LLC | Phoenix | Arizona | 85014 | — |
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85016 | — |
| Retina Associates Southwest PC | Tucson | Arizona | 85704 | — |
| California Retina Consultants. | Bakersfield | California | 93309 | — |
| Retina-Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Retinal Diagnostic Center | Campbell | California | 95008 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Eye Medical Center | Fresno | California | 93720 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835-3424 | — |
| Southern California Permanente Medical Group | Los Angeles | California | 90027 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| East Bay Retina Consultants | Oakland | California | 94609 | — |
| Southern CA Desert Retina Cons | Palm Desert | California | 92211 | — |
| California Eye Specialists Medical group Inc. | Pasadena | California | 91107 | — |
| Retina Consultants, San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92373 | — |
| Retinal Consultants Med Group | Sacramento | California | 95825 | — |
| West Coast Retina Medical Group | San Francisco | California | 94109 | — |
| Orange County Retina Med Group | Santa Ana | California | 92705 | — |
| California Retina Consultants | Santa Barbara | California | 93103 | — |
| California Retina Consultants - Santa Maria | Santa Maria | California | 93454 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| University of Colorado; dept of ophthalmology | Aurora | Colorado | 80045 | — |
| Retina Consultants of Southern | Colorado Springs | Colorado | 80909 | — |
| Colorado Retina Associates, PC | Lakewood | Colorado | 80228 | — |
| Retina Group of New England | Waterford | Connecticut | 06385 | — |
| Rand Eye | Deerfield Beach | Florida | 33064 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| National Ophthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Retina Care Specialists | Palm Beach Gardens | Florida | 33410 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Vitreous Assoc of FL | St. Petersburg | Florida | 33711 | — |
| Southern Vitreoretinal Assoc | Tallahassee | Florida | 32308 | — |
| Retina Associates of Florida, LLC | Tampa | Florida | 33609 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina PC | Marietta | Georgia | 30060-1137 | — |
| Retina Consultants of Hawaii | ‘Aiea | Hawaii | 96701 | — |
| University Retina and Macula Associates, PC | Oak Forest | Illinois | 60452 | — |
| Prairie Eye & LASIK Center / Prairie Retina Center | Springfield | Illinois | 62704 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Wolfe Eye Clinic | West Des Moines | Iowa | 50266 | — |
| Retina Associates | Lenexa | Kansas | 66215 | — |
| Vitreo-Retinal Consultants | Wichita | Kansas | 67214 | — |
| Retina Associates of Kentucky | Lexington | Kentucky | 40509 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| Johns Hopkins Med; Wilmer Eye Inst | Baltimore | Maryland | 21287 | — |
| Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina PC | Hagerstown | Maryland | 21740 | — |
| Retina Specialists | Towson | Maryland | 21204 | — |
| Tufts Medical Center; Ophthalmology | Boston | Massachusetts | 02111 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Beetham Eye Institute, Joslin Diabetes Center | Boston | Massachusetts | 02215 | — |
| Vitreo-Retinal Associates, PC | Worcester | Massachusetts | 01605 | — |
| Associated Retinal Consultants | Grand Rapids | Michigan | 49546 | — |
| Foundation for Vision Research | Grand Rapids | Michigan | 49546 | — |
| Vitreo-Retinal Associates | Grand Rapids | Michigan | 49546 | — |
| Assoc Retinal Consultants PC | Royal Oak | Michigan | 48073 | — |
| Associated Retinal Consultants, P.C. | Traverse City | Michigan | 49686 | — |
| VitreoRetinal Surgery, PLLC.; DBA Retina Consultants of Minnesota | Edina | Minnesota | 55435 | — |
| Midwest Vision Research Foundation | Chesterfield | Missouri | 63017 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| NJRetina | Edison | New Jersey | 08820 | — |
| Retinal & Ophthalmic Cons PC | Northfield | New Jersey | 08225 | — |
| Retina Associates of NJ | Teaneck | New Jersey | 07666 | — |
| University of New Mexico | Albuquerque | New Mexico | 87131 | — |
| Capital Region Retina | Albany | New York | 12206 | — |
| Long Is. Vitreoretinal Consult | Great Neck | New York | 11021 | — |
| Long Is. Vitreoretinal Consult | Hauppauge | New York | 11788 | — |
| Retina Vit Surgeons/Central NY | Liverpool | New York | 13088 | — |
| New York University | New York | New York | 10017 | — |
| Ophthalmic Cons of Long Island | Oceanside | New York | 11572 | — |
| Retina Associates of Western New York | Rochester | New York | 14620 | — |
| Island Retina | Shirley | New York | 11967 | — |
| The Retina Consultants | Slingerlands | New York | 12159 | — |
| Western Carolina Retinal Associate PA | Asheville | North Carolina | 28803 | — |
| Char Eye Ear &Throat Assoc | Charlotte | North Carolina | 28210 | — |
| Graystone Eye | Hickory | North Carolina | 28602 | — |
| Wake Forest Baptist Health Eye Centre | Winston-Salem | North Carolina | 27157 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Retina Assoc of Cleveland Inc | Cleveland | Ohio | 44122 | — |
| Cleveland Clinic Foundation; Cole Eye Institute | Cleveland | Ohio | 44195-0001 | — |
| The Ohio State University Havener Eye Institute | Columbus | Ohio | 43212 | — |
| Midwest Retina | Dublin | Ohio | 43016 | — |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | — |
| Retina Northwest | Portland | Oregon | 97221 | — |
| Mid Atlantic Retina - Wills Eye Hospital | Philadelphia | Pennsylvania | 19107 | — |
| Mid-Atlantic Retina | Philadelphia | Pennsylvania | 19107 | — |
| Retina Consultants Of Carolina | Greenville | South Carolina | 29605 | — |
| Charleston Neuroscience Inst | Ladson | South Carolina | 29456 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | — |
| Southeastern Retina Associates Chattanooga | Chattanooga | Tennessee | 37421 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| Retina Res Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Retina Associates | Austin | Texas | 78705-1169 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Retina & Vitreous of Texas | Bellaire | Texas | 77401-3510 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Valley Retina Institute P.A. | Harlingen | Texas | 78550 | — |
| Medical Center Ophthalmology Associates | San Antonio | Texas | 78240 | — |
| Retina Center of Texas | Southlake | Texas | 76092 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384-4167 | — |
| Eye Care Assoc of East Texas | Tyler | Texas | 75701 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Retina Associates of Utah, PLLC | Salt Lake City | Utah | 84107 | — |
| University of Utah; Division of Gastroenterology/Hepatology | Salt Lake City | Utah | 84132 | — |
| Uni of Vermont Medical Center; | Burlington | Vermont | 05405 | — |
| Univ of Virginia Ophthalmology | Charlottesville | Virginia | 22903 | — |
| Emerson Clinical Research Institute | Falls Church | Virginia | 22042 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Wagner Kapoor Institute | Norfolk | Virginia | 23502 | — |
| Retina Institute of Virginia | Richmond | Virginia | 23235 | — |
| West Virginia University Eye Institute | Morgantown | West Virginia | 26506 | — |
| University of Wisconsin | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 201 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04432831, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 8, 2026 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04432831 live on ClinicalTrials.gov.