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Completed Phase 2 Interventional Results available

A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia

ClinicalTrials.gov ID: NCT04435431

Public ClinicalTrials.gov record NCT04435431. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 1, 2026, 10:22 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Placebo-controlled Phase IIB Study Evaluating the Efficacy of Mesdopetam on Daily ON-time Without Troublesome Dyskinesia in Patients With Parkinson's Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2b study investigating the efficacy and safety of mesdopetam as adjunct therapy on daily ON-time without troublesome dyskinesia in patients with Parkinson disease. Mesdopetam is taken for 84 days.

Study identification

NCT ID
NCT04435431
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Enrollment
155 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
30 Years to 79 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 28, 2020
Primary completion
Dec 1, 2022
Completion
Dec 8, 2022
Last update posted
Mar 5, 2024

2020 – 2022

United States locations

U.S. sites
14
U.S. states
9
U.S. cities
12
Facility City State ZIP Site status
Movement Disorders Center of Arizona Scottsdale Arizona 85258
Collaborative Neuroscience Research (CNS Research) Long Beach California 90806
Parkinson's Disease and Movement Disorders Center of Silicon Valley Palo Alto California 94301
Colorado Springs Neurological Associates Colorado Springs Colorado 80907
Parkinson's Disease and Movement Disorders Center of Boca Raton Boca Raton Florida 33486
Avantis Clinical Research Miami Florida 33155
Elias Research Associates (Allied Biomedical Research Institute) Miami Florida 33155
Pharmax Research of South Florida, Inc. Miami Florida 33175
Life Medical Research Group Corp Miami Gardens Florida 33014
NeuroStudies.net, LLC Decatur Georgia 30030
University of Kentucky, Department of Neurology Lexington Kentucky 40536
The Movement Disorder Clinic of Oklahoma Tulsa Oklahoma 74136
University of Texas Southwestern Medical Center Dallas Texas 75390
Inland Northwest Research Spokane Washington 99202

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04435431, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 5, 2024 · Synced Sep 1, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04435431 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →