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Completed Phase 3 Interventional Results available

A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD)

ClinicalTrials.gov ID: NCT04442490

Public ClinicalTrials.gov record NCT04442490. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 11:48 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Evaluating the Efficacy of SAGE-217 in the Treatment of Adult Subjects With Major Depressive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study to evaluate the efficacy of SAGE-217 in the treatment of participants with MDD.

Study identification

NCT ID
NCT04442490
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Biogen
Industry
Enrollment
543 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 64 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 11, 2020
Primary completion
Mar 25, 2021
Completion
Apr 20, 2021
Last update posted
Dec 21, 2023

2020 – 2021

United States locations

U.S. sites
39
U.S. states
18
U.S. cities
37
Facility City State ZIP Site status
Sage Investigational Site Rogers Arkansas 72758
Sage Investigational Site Bellflower California 90706
Sage Investigational Site Garden Grove California 92845
Sage Investigational Site Glendale California 91206
Sage Investigational Site Lemon Grove California 91945
Sage Investigational Site Orange California 92868
Sage Investigational Site Pico Rivera California 90660
Sage Investigational Site Redlands California 92374
Sage Investigational Site San Diego California 92103
Sage Investigational Site Sherman Oaks California 91403
Sage Investigational Site Temecula California 92591
Sage Investigational Site Coral Springs Florida 33067
Sage Investigational Site Hollywood Florida 33024
Sage Investigational Site Jacksonville Florida 32256
Sage Investigational Site Lauderhill Florida 33319
Sage Investigational Site Orange City Florida 32763
Sage Investigational Site Orlando Florida 32801
Sage Investigational Site Orlando Florida 32807
Sage Investigational Site Alpharetta Georgia 30022
Sage Investigational Site Atlanta Georgia 30328
Sage Investigational Site Atlanta Georgia 30331
Sage Investigational Site Decatur Georgia 30030
Sage Investigational Site Skokie Illinois 60076
Sage Investigational Site Flowood Mississippi 39232
Sage Investigational Site O'Fallon Missouri 63368
Sage Investigational Site Las Vegas Nevada 89102
Sage Investigational Site Marlton New Jersey 08053
Sage Investigational Site Charlotte North Carolina 28211
Sage Investigational Site Cincinnati Ohio 45215
Sage Investigational Site Dayton Ohio 45417
Sage Investigational Site North Canton Ohio 44720
Sage Investigational Site Oklahoma City Oklahoma 73112
Sage Investigational Site Portland Oregon 97210
Sage Investigational Site Allentown Pennsylvania 18104
Sage Investigational Site Charleston South Carolina 29407
Sage Investigational Site Memphis Tennessee 38119
Sage Investigational Site DeSoto Texas 75115
Sage Investigational Site Wichita Falls Texas 76309
Sage Investigational Site Charlottesville Virginia 22903

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04442490, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 21, 2023 · Synced Sep 2, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04442490 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →