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Completed Phase 3 Interventional Results available

A Study of Long-Term Safety and Efficacy of Lanadelumab for Prevention of Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor

ClinicalTrials.gov ID: NCT04444895

Public ClinicalTrials.gov record NCT04444895. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 9:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label Study to Evaluate the Long-Term Safety and Efficacy of Lanadelumab for Prevention Against Acute Attacks of Non-histaminergic Angioedema With Normal C1-Inhibitor (C1-INH)

Study identification

NCT ID
NCT04444895
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Shire
Industry
Enrollment
73 participants

Conditions and interventions

Conditions

Interventions

  • Lanadelumab Drug

Drug

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 4, 2021
Primary completion
May 4, 2023
Completion
May 4, 2023
Last update posted
Jun 16, 2024

2021 – 2023

United States locations

U.S. sites
15
U.S. states
13
U.S. cities
15
Facility City State ZIP Site status
Clinical Research Center of Alabama Birmingham Alabama 35209
Medical Research of Arizona Scottsdale Arizona 85248
UCSD Angioedema Center San Diego California 92122
Allergy and Asthma Clinical Research Inc Walnut Creek California 94598
Asthma and Allergy Associates, PC Colorado Springs Colorado 80907
Rush University Medical Center Chicago Illinois 60612
Kanarek Allergy, Asthma and Immunology Overland Park Kansas 66211
Institute for Asthma & Allergy, P.C. Chevy Chase Maryland 20815
Massachusetts General Hospital Boston Massachusetts 02114
University of Michigan Ann Arbor Michigan 48106
Mayo Clinic Rochester Minnesota 55905
Washington University St Louis Missouri 63141
Bernstein Clinical Research Center, LLC Cincinnati Ohio 45236
Optimed Research, LTD Columbus Ohio 43235
Seattle Allergy & Asthma Research Institute Seattle Washington 98115

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04444895, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 16, 2024 · Synced Jul 22, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04444895 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →