Safety of Sildenafil in Premature Infants With Severe Bronchopulmonary Dysplasia
Public ClinicalTrials.gov record NCT04447989. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a multicenter, randomized, placebo-controlled, sequential dose-escalating, double-masked, safety study of sildenafil in premature infants (inpatient in Neonatal Intensive Care Units (NICUs)) with severe bronchopulmonary dysplasia (BPD).
Study identification
- NCT ID
- NCT04447989
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 125 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- Up to 29 Weeks
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 27, 2021 (Actual)
- Primary completion
- Dec 12, 2024 (Actual)
- Completion
- Jan 15, 2025 (Actual)
- Last update posted
- Jan 26, 2026
2021 – 2025
United States locations
- U.S. sites
- 25
- U.S. states
- 17
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arkansas Children's Research Institute | Little Rock | Arkansas | 72202 | — |
| University of Arkansas Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Rady Children's Hospital and Health Center | San Diego | California | 92123 | — |
| Childrens National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| University of Florida Jacksonville Shands Medical Center | Jacksonville | Florida | 32209 | — |
| Wolfson Children's Hospital | Jacksonville | Florida | 32209 | — |
| Emory Children's Center | Atlanta | Georgia | 30322 | — |
| Lurie Children's Hospital | Chicago | Illinois | 60611-2605 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60611 | — |
| University of Kentucky Chandler Medical Center | Lexington | Kentucky | 40506 | — |
| University of Louisville School of Medicine | Louisville | Kentucky | 40202 | — |
| Ochsner Baptist Medical Center | New Orleans | Louisiana | 70115 | — |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Childrens Mercy Hospital | Kansas City | Missouri | 64108 | — |
| Children's Hospital of Nevada at University Medical Center | Las Vegas | Nevada | 89102 | — |
| University of Rochester School of Medicine Children's Hospital | Rochester | New York | 14642 | — |
| Westchester Medical Center - New York Medical College | Valhalla | New York | 10595 | — |
| University of NC at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| East Carolina University | Greenville | North Carolina | 27858 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Rainbow Babies and Childrens Hospital | Cleveland | Ohio | 44106 | — |
| University of Tennessee Health Science Center | Memphis | Tennessee | 38163 | — |
| University of Texas Health | Austin | Texas | 78723 | — |
| Women's Hospital of Texas | Houston | Texas | 77054 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04447989, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 26, 2026 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04447989 live on ClinicalTrials.gov.