A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)
Public ClinicalTrials.gov record NCT04451330. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Randomized, Double-Blind, Placebo Controlled Study To Compare Efficacy and Safety of Trifarotene (CD5789) Cream When Used Withan Oral Antibiotic for the Treatment of Severe Acne Vulgaris
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study was to demonstrate that daily use of topical trifarotene (CD5789) 50 microgram per gram (mcg/g) cream when used in association with oral antibiotic is safe and effective for the treatment of severe AV.
Study identification
- NCT ID
- NCT04451330
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 202 participants
Conditions and interventions
Conditions
Interventions
- Trifarotene cream Drug
- Doxycycline hyclate Drug
- Trifarotene Vehicle Drug
- Doxycycline Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 29, 2020 (Actual)
- Primary completion
- Apr 26, 2021 (Actual)
- Completion
- Apr 26, 2021 (Actual)
- Last update posted
- May 10, 2022
2020 – 2021
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Galderma Investigational Site | Fort Smith | Arkansas | 72916 | — |
| Galderma Investigational Site | Hot Springs | Arkansas | 71913 | — |
| Galderma Investigational Site | Rogers | Arkansas | 72758 | — |
| Galderma Investigational Site | Newport Beach | California | 92663 | — |
| Galderma Investigational Site | Aventura | Florida | 33180 | — |
| Galderma Investigational Site | Boca Raton | Florida | 33486 | — |
| Galderma Investigational Site | Miramar | Florida | 33027 | — |
| Galderma Investigational Site | Newnan | Georgia | 30263 | — |
| Galderma Investigational Site | Evansville | Indiana | 47715 | — |
| Galderma Investigational Site | New Albany | Indiana | 47150 | — |
| Galderma Investigational Site | Rockville | Maryland | 20850 | — |
| Galderma Investigational Site | Warren | Michigan | 48088 | — |
| Galderma Investigational Site | New Brighton | Minnesota | 55112 | — |
| Galderma Investigational Site | Las Vegas | Nevada | 89148 | — |
| Galderma Investigational Site | Stony Brook | New York | 11790 | — |
| Galderma Investigational Site | High Point | North Carolina | 27262 | — |
| Galderma Investigational Site | Sugarloaf | Pennsylvania | 18249 | — |
| Galderma Investigational Site | Charleston | South Carolina | 71913 | — |
| Galderma Investigational Site | Knoxville | Tennessee | 37922 | — |
| Galderma Investigational Site | Arlington | Texas | 76011 | — |
| Galderma Investigational Site | Dallas | Texas | 75246 | — |
| Galderma Investigational Site | Grapevine | Texas | 76051 | — |
| Galderma Investigational Site | Pflugerville | Texas | 78660 | — |
| Galderma Investigational Site | San Antonio | Texas | 78218 | — |
| Galderma Investigational Site | San Antonio | Texas | 78249 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04451330, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 10, 2022 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04451330 live on ClinicalTrials.gov.