Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure
Public ClinicalTrials.gov record NCT04452149. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The ALLEVIATE-HF study is a prospective, randomized, controlled, blinded, multi-site, interventional, investigational device exemption (IDE) pivotal study. The purpose of the study is to demonstrate the safety and efficacy of a patient management pathway that utilizes an integrated device diagnostic-based risk stratification algorithm to guide patient care in subjects with NYHA class II and III heart failure, and to demonstrate the safety of the Reveal LINQ™ system and procedure in the study population.
Study identification
- NCT ID
- NCT04452149
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 826 participants
Conditions and interventions
Interventions
- Reveal LINQ™ Insertable Cardiac Monitor with investigational ALLEVIATE-HF RAMware download Device
- Medication intervention Other
- Not Randomized to Device or Medication Intervention Other
Device · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 3, 2020 (Actual)
- Primary completion
- Jun 2, 2025 (Actual)
- Completion
- Jun 2, 2025 (Actual)
- Last update posted
- Aug 26, 2026
2020 – 2025
United States locations
- U.S. sites
- 53
- U.S. states
- 26
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cardiovascular Associates of Mesa | Mesa | Arizona | 85282 | — |
| Arrhythmia Research Group | Jonesboro | Arkansas | 72410 | — |
| Saint Joseph Heritage Healthcare | Mission Viejo | California | 92691 | — |
| Cardiology Associates Medical Group | Oxnard | California | 93030 | — |
| Saint Joseph's Medical Center | Stockton | California | 95204 | — |
| South Denver Cardiology Associates | Littleton | Colorado | 80120 | — |
| FWD Clinical Research LLC | Boca Raton | Florida | 33486 | — |
| Bay Area Cardiology Associates PA | Brandon | Florida | 33511 | — |
| Florida Heart Center | Ft. Pierce | Florida | 34950 | — |
| Baptist Health | Jacksonville | Florida | 32207 | — |
| First Coast Cardiovascular Institute PA | Jacksonville | Florida | 32256 | — |
| Citrus Cardiology Consultants PA | Leesburg | Florida | 34748 | — |
| Baptist Hospital | Pensacola | Florida | 32501 | — |
| Northside Hospital | St. Petersburg | Florida | 33709 | — |
| Tallahassee Research Institute | Tallahassee | Florida | 32308 | — |
| Memorial Health University Medical Center | Savannah | Georgia | 31404 | — |
| NorthShore University Health System | Evanston | Illinois | 60201 | — |
| Carle Foundation Hospital | Urbana | Illinois | 61801 | — |
| Parkview Health | Fort Wayne | Indiana | 46845 | — |
| Ascension Medical Group - Saint Vincent | Indianapolis | Indiana | 46260 | — |
| Iowa Heart Center | West Des Moines | Iowa | 50266 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Saint Elizabeth Healthcare | Edgewood | Kentucky | 41017 | — |
| Baptist Healthcare System | Louisville | Kentucky | 40207 | — |
| Norton Healthcare | Louisville | Kentucky | 40217 | — |
| North Memorial Health Heart & Vascular Center | Robbinsdale | Minnesota | 55422 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Cardiology Associates of North Mississippi | Tupelo | Mississippi | 38801 | — |
| CHI Health Creighton University Medical Center - Bergan Mercy | Omaha | Nebraska | 68124 | — |
| Lourdes Cardiology Services | Voorhees Township | New Jersey | 08043 | — |
| New Mexico Heart Institute PA | Albuquerque | New Mexico | 87102 | — |
| Columbia University Irving Medical Center/NYPH | New York | New York | 10032 | — |
| Hudson Valley Heart Center | Poughkeepsie | New York | 12601 | — |
| Saint Francis Hospital | Roslyn | New York | 11576 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Cone Health | Greensboro | North Carolina | 27401 | — |
| Novant Health New Hanover Regional Medical Center | Wilmington | North Carolina | 28401 | — |
| The Lindner Research Center | Cincinnati | Ohio | 45219 | — |
| Mount Carmel East | Columbus | Ohio | 43213 | — |
| OhioHealth Research and Innovation Institute (OHRI) | Columbus | Ohio | 43214 | — |
| Doylestown Health Cardiology a division of Doylestown Health Physicians | Doylestown | Pennsylvania | 18901 | — |
| Cardiology Consultants of Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Prisma Health Midlands | Columbia | South Carolina | 29203 | — |
| The Stern Cardiovascular Foundation | Germantown | Tennessee | 38138 | — |
| University of Tennessee Methodist Physicians | Memphis | Tennessee | 38104 | — |
| Medical City Fort Worth | Fort Worth | Texas | 76104 | — |
| Tyler Cardiovascular Consultants | Tyler | Texas | 75701 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
| Swedish Medical Center Cherry Hill | Seattle | Washington | 98122 | — |
| Saint Joseph Medical Center (Tacoma WA) | Tacoma | Washington | 98405 | — |
| Charleston Area Medical Center (CAMC) Memorial Hospital | Charleston | West Virginia | 25304 | — |
| West Virginia University | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04452149, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 26, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04452149 live on ClinicalTrials.gov.