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Completed Phase 1 Interventional

A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors

ClinicalTrials.gov ID: NCT04452214

Public ClinicalTrials.gov record NCT04452214. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:35 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-label, Safety and Tolerability Phase 1b Trial of CAN04, a Fully Humanized Anti-IL1RAP Monoclonal Antibody, and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors

Study identification

NCT ID
NCT04452214
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1
Lead sponsor
Cantargia AB
Industry
Enrollment
19 participants

Conditions and interventions

Interventions

  • CAN04 Drug
  • Carboplatin Drug
  • Pembrolizumab Drug
  • Pemetrexed Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 23, 2020
Primary completion
Jun 27, 2023
Completion
Jun 27, 2023
Last update posted
Jul 13, 2023

2020 – 2023

United States locations

U.S. sites
3
U.S. states
3
U.S. cities
3
Facility City State ZIP Site status
University of Colorado Cancer Center Aurora Colorado 80045
Florida Cancer Specialists & Research Institute Lake Mary Florida 32746
Hospital of The University of Pennsylvania Philadelphia Pennsylvania 19104-5127

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04452214, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 13, 2023 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04452214 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →