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Completed Phase 2 Interventional Results available

Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Osteoarthritis

ClinicalTrials.gov ID: NCT04456686

Public ClinicalTrials.gov record NCT04456686. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 9:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Randomized, Placebo-Controlled, Phase 2 Clinical Trial to Evaluate LY3016859 for the Treatment of Osteoarthritis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study is being done to test the safety and efficacy of LY3016859 for the treatment of osteoarthritis pain. This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292) which is a protocol to accelerate the development of new treatments for chronic pain.

Study identification

NCT ID
NCT04456686
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
117 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 30, 2020
Primary completion
Apr 21, 2021
Completion
Aug 25, 2021
Last update posted
Nov 13, 2023

2020 – 2021

United States locations

U.S. sites
32
U.S. states
17
U.S. cities
31
Facility City State ZIP Site status
Simon Williamson Clinic Birmingham Alabama 35211 —
Synexus- Chandler Chandler Arizona 85224 —
Synexus Clinical Research - Glendale Glendale Arizona 85306 —
Irvine Clinical Research Center Irvine California 92614 —
Artemis Institute for Clinical Research Riverside California 92503 —
Artemis Institute for Clinical Research San Diego California 92103 —
Suncoast Research Group Miami Florida 33135 —
Renstar Medical Research Ocala Florida 34470 —
Synexus - US Orlando Florida 32806 —
Synexus - US Pinellas Park Florida 33781 —
Gold Coast Research Plantation Florida 33317 —
Synexus Clinical Research US, Inc - Orlando The Villages Florida 32162 —
Synexus Clinical Research Chicago Illinois 60602 —
Northwestern University Chicago Illinois 60611 —
Cotton O'Neil Infusion Center Topeka Kansas 66606 —
ActivMed Practices and Research Methuen Massachusetts 01844 —
MedVadis Research Corporation Waltham Massachusetts 02451 —
Great Lakes Research Group, Inc. Bay City Michigan 48706 —
StudyMetrix Research City of Saint Peters Missouri 63303 —
Synexus - US Omaha Nebraska 68144 —
PharmQuest Greensboro North Carolina 27408 —
Synexus - Cincinnati Cincinnati Ohio 45236 —
Rapid Medical Research Cleveland Ohio 44122 —
Aventiv Research Inc Columbus Ohio 43213 —
Altoona Center For Clinical Research Duncansville Pennsylvania 16635 —
Clinical Research Center of Reading,LLC Wyomissing Pennsylvania 19610 —
Coastal Carolina Research Center North Charleston South Carolina 29405 —
Synexus - US Dallas Texas 75234 —
Synexus - US San Antonio Texas 78229 —
Synexus - US Murray Utah 84123 —
Northwest Clinical Research Center Bellevue Washington 98007-4209 —
Rainier Clinical Research Center Renton Washington 98057 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04456686, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 13, 2023 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04456686 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →