Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
Public ClinicalTrials.gov record NCT04460872. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Locomotor Training With Testosterone to Promote Bone and Muscle Health
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete or complete spinal cord injury. The investigators hypothesize that LT+TRT treatment will improve muscle size and bone mineral density in men with low T and ambulatory dysfunction after incomplete or complete SCI, along with muscle fundtion and walking recovery in men with T low and ambulatory dysfunction ater incomplete SCI.
Study identification
- NCT ID
- NCT04460872
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 21 participants
Conditions and interventions
Conditions
- Spinal Cord Injury
- Spinal Cord Injuries
- Trauma, Nervous System
- Wounds and Injury
- Central Nervous System Diseases
- Spinal Cord Diseases
- Gonadal Disorders
- Endocrine System Diseases
- Hypogonadism
- Genital Diseases, Male
- Spinal Cord Trauma
- Injuries, Spinal Cord
- Walking, Difficulty
- Gait Disorders, Neurologic
- Locomotion Disorder, Neurologic
- Wounds and Injuries
- Nervous System Diseases
- Testosterone Deficiency
- Androgen Deficiency
- Hormone Deficiency
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2021
- Primary completion
- Jan 29, 2026
- Completion
- Jun 29, 2026
- Last update posted
- May 5, 2025
2021 – 2026
United States locations
- U.S. sites
- 2
- U.S. states
- 1
- U.S. cities
- 2
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| North Florida/South Georgia Veterans Health System | Gainesville | Florida | 32608 | Recruiting |
| Brooks Rehabilitation | Jacksonville | Florida | 32216 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04460872, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2025 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04460872 live on ClinicalTrials.gov.