Efficacy and Safety of Nerinetide in Participants With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy Excluding Thrombolysis
Public ClinicalTrials.gov record NCT04462536. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicentre, Randomized, Double-blinded, Placebo-controlled, Parallel Group, Single-dose Design to Determine the Efficacy and Safety of Nerinetide in Participants With Acute Ischemic Stroke Undergoing Endovascular Thrombectomy Excluding Thrombolysis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of this study is to determine if a single dose of nerinetide can reduce global disability in people who have had a stroke and are selected for endovascular therapy without the use of a tissue plasminogen activator (alteplase, tenecteplase, or equivalent).
Study identification
- NCT ID
- NCT04462536
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 850 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 6, 2020 (Actual)
- Primary completion
- Aug 31, 2023 (Actual)
- Completion
- Aug 31, 2023 (Actual)
- Last update posted
- Jun 22, 2025
2020 – 2023
United States locations
- U.S. sites
- 17
- U.S. states
- 14
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| St. Joseph's Hospital & Medical Center | Phoenix | Arizona | 85013 | — |
| Providence Little Company of Mary Medical Center - Torrance | Torrance | California | 90503 | — |
| Swedish Medical Center | Englewood | Colorado | 80113 | — |
| Baptist Health Research Institute | Jacksonville | Florida | 32207 | — |
| University of Miami, Jackson Memorial Hospital | Miami | Florida | 33136 | — |
| Grady Memorial Hospital | Atlanta | Georgia | 30303 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| University of Massachusetts Medical School | Worcester | Massachusetts | 01655 | — |
| NYU Langone Hospital Brooklyn | Brooklyn | New York | 11220 | — |
| Montefiore Medical Center | The Bronx | New York | 10467 | — |
| The Ohio State University, Wexner Medical Center Neurological Surgery | Columbus | Ohio | 43203 | — |
| Providence St. Vincent Medical Center | Portland | Oregon | 97225 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| UPMC Stroke Institute | Pittsburgh | Pennsylvania | 15213 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903-4923 | — |
| Valley Baptist Medical Center - Harlingen | Harlingen | Texas | 78550 | — |
| Swedish Medical Center - Cherry Hill Campus | Seattle | Washington | 98122 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 64 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04462536, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2025 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04462536 live on ClinicalTrials.gov.