ClinicalTrials.gov record
A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19
ClinicalTrials.gov ID: NCT04470427
Public ClinicalTrials.gov record NCT04470427. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine in Adults Aged 18 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The mRNA-1273 vaccine is being developed to prevent COVID-19, the disease resulting from Severe Acute Respiratory Syndrome coronavirus (SARS-CoV-2) infection. The study is designed to primarily evaluate the efficacy, safety, and immunogenicity of mRNA-1273 to prevent COVID-19 for up to 2 years after the second dose of mRNA-1273.
Study identification
- NCT ID
- NCT04470427
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 30,415 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 26, 2020
- Primary completion
- Dec 28, 2022
- Completion
- Dec 28, 2022
- Last update posted
- Mar 20, 2024
2020 – 2022
United States locations
- U.S. sites
- 100
- U.S. states
- 31
- U.S. cities
- 82
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Ascension St. Vincent Birmingham | Birmingham | Alabama | 35205 | — |
| Synexus Clinical Research US, Inc. - Birmingham | Birmingham | Alabama | 35211 | — |
| Hope Research Institute | Chandler | Arizona | 85224 | — |
| Synexus Clinical Research US, Inc. - Phoenix West | Glendale | Arizona | 85306 | — |
| Hope Research Institute | Peoria | Arizona | 85018 | — |
| Hope Research Institute | Phoenix | Arizona | 85018 | — |
| Quality of Life Medical and Research Center | Tucson | Arizona | 85712 | — |
| Baptist Health Center for Clinical Research | Little Rock | Arkansas | 72205 | — |
| Advanced Clinical Research - Rancho Paseo | Banning | California | 92220 | — |
| University of California San Diego | La Jolla | California | 92093 | — |
| eStudySite - La Mesa | La Mesa | California | 91942 | — |
| UCLA Vine Street Clinic CRS | Los Angeles | California | 90038 | — |
| VA Greater Los Angeles Healthcare (veterans only) | Los Angeles | California | 90073 | — |
| Paradigm Clinical Research Institute Inc | Redding | California | 96001 | — |
| Benchmark Research - Sacramento | Sacramento | California | 95864 | — |
| Medical Center For Clinical Research - M3 Wake Research | San Diego | California | 92108 | — |
| University of Colorado Hospital | Aurora | Colorado | 80045 | — |
| Lynn Institute of The Rockies | Colorado Springs | Colorado | 80918 | — |
| George Washington University | Washington D.C. | District of Columbia | 20037 | — |
| Accel Research Site | DeLand | Florida | 32720 | — |
| Research Centers of America | Hollywood | Florida | 33024 | — |
| Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| Synexus - Optimal Research - Melbourne | Melbourne | Florida | 32934 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| University of Miami | Miami | Florida | 33136 | — |
| Synexus Clinical Research US, Inc. - Orlando | Orlando | Florida | 32806 | — |
| Palm Beach Research Center | West Palm Beach | Florida | 33409 | — |
| Grady Health System | Atlanta | Georgia | 30303 | — |
| Children's Healthcare of Atlanta | Atlanta | Georgia | 30322 | — |
| Hope Clinic of The Emory Vaccine Center | Decatur | Georgia | 30030 | — |
| Meridian Clinical Research | Savannah | Georgia | 31406 | — |
| Clinical Research Atlanta | Stockbridge | Georgia | 30281 | — |
| Synexus Clinical Research US, Inc. - Chicago | Chicago | Illinois | 60602 | — |
| UIC Project WISH CRS | Chicago | Illinois | 60612 | — |
| University of Chicago-Hospital | Chicago | Illinois | 60637 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219 | — |
| Alliance for Multispecialty Research | Newton | Kansas | 67114 | — |
| Alliance for Multispecialty Research- East Wichita | Wichita | Kansas | 67207 | — |
| Meridian Clinical Research | Baton Rouge | Louisiana | 70808 | — |
| Benchmark Research - Metairie | Metairie | Louisiana | 70006 | — |
| University of Maryland School of Medicine | Baltimore | Maryland | 21201 | — |
| Synexus - Optimal Research - Rockville | Rockville | Maryland | 20850 | — |
| Meridian Clinical Research | Rockville | Maryland | 20854 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| MediSync Clinical Research Hattiesburg Clinic | Petal | Mississippi | 39465 | — |
| Saint Louis University | St Louis | Missouri | 63104 | — |
| Sundance Clinical Research | St Louis | Missouri | 63141 | — |
| Meridian Clinical Research | Grand Island | Nebraska | 68803 | — |
| Meridian Clinical Research | Norfolk | Nebraska | 68701 | — |
| Meridian Clinical Research | Omaha | Nebraska | 68134 | — |
| Clinical Research Center of Nevada | Las Vegas | Nevada | 89104 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| New Jersey Medical School | Newark | New Jersey | 07103 | — |
| Meridian Clinical Research | Binghamton | New York | 13901 | — |
| Weill Cornell Chelsea - (CRS) | New York | New York | 10010 | — |
| Weill Cornell Medical College | New York | New York | 10065 | — |
| University of North Carolina at Chapel Hill | Chapel Hill | North Carolina | 27599 | — |
| Tryon Medical Partners | Charlotte | North Carolina | 28210 | — |
| Carolina Institute for Clinical Research - M3 Wake Research | Fayetteville | North Carolina | 28304 | — |
| M3 Wake Research, Inc - M3 Wake | Raleigh | North Carolina | 27612 | — |
| Trial Management Associates | Wilmington | North Carolina | 28403 | — |
| Wake Forest University Health Sciences | Winston-Salem | North Carolina | 27157 | — |
| Synexus Clinical Research US, Inc. - Cincinnati | Cincinnati | Ohio | 45236 | — |
| New Horizons Clinical Research | Cincinnati | Ohio | 45242 | — |
| Cincinnati CRS | Cincinnati | Ohio | 45267 | — |
| Rapid Medical Research Inc | Cleveland | Ohio | 44122 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Crisor | Medford | Oregon | 97504 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| UPMC University Center | Pittsburgh | Pennsylvania | 15213 | — |
| Keystone VitaLink Research | Anderson | South Carolina | 29621 | — |
| Keystone VitaLink Research - Greenville | Greenville | South Carolina | 29615 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| Keystone VitaLink Research - Spartanburg | Spartanburg | South Carolina | 29303 | — |
| Meridian Clinical Research | Dakota Dunes | South Dakota | 57049 | — |
| WR-ClinSearch | Chattanooga | Tennessee | 37421 | — |
| Alliance for Multispecialty Research | Knoxville | Tennessee | 39720 | — |
| Vanderbilt University Medical Center, Medical Arts Building | Nashville | Tennessee | 37232 | — |
| Vanderbilt University Medical Center, Medical Center North | Nashville | Tennessee | 37232 | — |
| Benchmark Research - Austin | Austin | Texas | 78705 | — |
| Synexus - Optimal Research - Austin | Austin | Texas | 78705 | — |
| Tekton Research | Austin | Texas | 78745 | — |
| Advanced Clinical Research - Be Well MD | Cedar Park | Texas | 78613 | — |
| Global Medical Research - M3 Wake Research | Dallas | Texas | 75224 | — |
| Synexus Clinical Research US, Inc. - Dallas | Dallas | Texas | 75234 | — |
| Benchmark Research - Fort Worth | Fort Worth | Texas | 76135 | — |
| University of Texas Medical Branch at Galveston | Galveston | Texas | 77555 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| DM Clinical Research - Texas Center For Drug Development | Houston | Texas | 77081 | — |
| Laguna Clinical Research | Laredo | Texas | 78041 | — |
| Centex Studies | McAllen | Texas | 78504 | — |
| Benchmark Research - San Angelo | San Angelo | Texas | 76904 | — |
| Clinical Trials of Texas, Inc | San Antonio | Texas | 78229 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
| Synexus Clinical Research US, Inc. - Salt Lake City | Murray | Utah | 84123 | — |
| Foothill Family Clinic - North | Salt Lake City | Utah | 84109 | — |
| Foothill Family Clinic-South Clinic | Salt Lake City | Utah | 84121 | — |
| Kaiser Permanente - Seattle | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
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About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04470427, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 20, 2024 · Synced Sep 3, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04470427 live on ClinicalTrials.gov.