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Terminated Phase 2 Interventional Results available

A Study of IMR-687 in Subjects With Sickle Cell Disease

ClinicalTrials.gov ID: NCT04474314

Public ClinicalTrials.gov record NCT04474314. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects With Sickle Cell Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease

Study identification

NCT ID
NCT04474314
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cardurion Pharmaceuticals, Inc.
Industry
Enrollment
115 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 13, 2020 (Actual)
Primary completion
Mar 2, 2022 (Actual)
Completion
May 4, 2022 (Actual)
Last update posted
May 15, 2025

2020 – 2022

United States locations

U.S. sites
14
U.S. states
12
U.S. cities
14
Facility City State ZIP Site status
University of Alabama at Birmingham School of Medicine - 1917 Clinic Birmingham Alabama 35233 —
Arkansas Primary Care Clinic Little Rock Arkansas 72204 —
University of California San Diego Moores Cancer Center La Jolla California 92093 —
Center For Inherited Blood Disorders Santa Ana California 92705 —
The Oncology Institute Long Beach Whittier California 90603 —
University of Connecticut Health Main Building Farmington Connecticut 06030 —
Children's Healthcare of Atlanta Atlanta Georgia 30342 —
The University of Illinois at Chicago College of Medicine Chicago Illinois 60612-4333 —
Johns Hopkins Hospital Baltimore Maryland 21287 —
Children's Hospital of Michigan Detroit Michigan 48201 —
Newark Beth Israel Medical Center Newark New Jersey 07112 —
Weill Cornell Medicine - Center for Blood Disorders New York New York 10021 —
Baylor Scott & White Medical Center-Temple Temple Texas 76508 —
Virginia Commonwealth University Health - Ambulatory Care Center Richmond Virginia 23219 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 35 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04474314, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 15, 2025 · Synced Oct 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04474314 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →