A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder
Public ClinicalTrials.gov record NCT04476030. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind Study Comparing the Efficacy and Safety of SAGE-217 Plus an Antidepressant Versus Placebo Plus an Antidepressant in Adults With Major Depressive Disorder
Study identification
- NCT ID
- NCT04476030
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Biogen
- Industry
- Enrollment
- 440 participants
Conditions and interventions
Conditions
Interventions
- Citalopram Drug
- Desvenlafaxine Drug
- Duloxetine Drug
- Escitalopram Drug
- Matching Placebo Drug
- SAGE-217 Drug
- Sertraline Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 64 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 8, 2020
- Primary completion
- Oct 24, 2021
- Completion
- Dec 21, 2021
- Last update posted
- Dec 21, 2023
2020 – 2021
United States locations
- U.S. sites
- 51
- U.S. states
- 21
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sage Investigational Site | Dothan | Alabama | 36303 | — |
| Sage Investigational Site | Phoenix | Arizona | 85012 | — |
| Sage Investigational Site | Anaheim | California | 92805 | — |
| Sage Investigational Site | Costa Mesa | California | 92626 | — |
| Sage Investigational Site | Glendale | California | 91206 | — |
| Sage Investigational Site | Irvine | California | 92614 | — |
| Sage Investigational Site | Los Alamitos | California | 90720 | — |
| Sage Investigational Site | Oceanside | California | 92056 | — |
| Sage Investigational Site | Orange | California | 92868 | — |
| Sage Investigational Site | Riverside | California | 92503 | — |
| Sage Investigational Site | San Diego | California | 92103 | — |
| Sage Investigational Site | Temecula | California | 92591 | — |
| Sage Investigational Site | Colorado Springs | Colorado | 80910 | — |
| Sage Investigational Site | Cromwell | Connecticut | 06416 | — |
| Sage Investigational Site | Norwich | Connecticut | 06360 | — |
| Sage Investigational Site | Coral Springs | Florida | 33067 | — |
| Sage Investigational Site | Jacksonville | Florida | 32256 | — |
| Sage Investigational Site | Orlando | Florida | 32801 | — |
| Sage Investigational Site | Orlando | Florida | 32807 | — |
| Sage Investigational Site | Pensacola | Florida | 32502 | — |
| Sage Investigational Site | Alpharetta | Georgia | 30022 | — |
| Sage Investigational Site | Atlanta | Georgia | 30331 | — |
| Sage Investigational Site | Marietta | Georgia | 30060 | — |
| Sage Investigational Site | Savannah | Georgia | 31405 | — |
| Sage Investigational Site | Chicago | Illinois | 60634 | — |
| Sage Investigational Site | Chicago | Illinois | 60640 | — |
| Sage Investigational Site | Towson | Maryland | 21204 | — |
| Sage Investigational Site | Watertown | Massachusetts | 02472 | — |
| Sage Investigational Site | Ann Arbor | Michigan | 48109 | — |
| Sage Investigational Site | Saint Charles | Missouri | 63304 | — |
| Sage Investigational Site | Lincoln | Nebraska | 68526 | — |
| Sage Investigational Site | Cherry Hill | New Jersey | 08002 | — |
| Sage Investigational Site | Marlton | New Jersey | 08053 | — |
| Sage Investigational Site | Princeton | New Jersey | 08540 | — |
| Sage Investigational Site | Albuquerque | New Mexico | 87109 | — |
| Sage Investigational Site | Brooklyn | New York | 11229 | — |
| Sage Investigational Site | Brooklyn | New York | 11235 | — |
| Sage Investigational Site | Mount Kisco | New York | 10549 | — |
| Sage Investigational Site | Beachwood | Ohio | 44122 | — |
| Sage Investigational Site | Cincinnati | Ohio | 45212 | — |
| Sage Investigational Site | Cincinnati | Ohio | 45215 | — |
| Sage Investigational Site | Cincinnati | Ohio | 45219 | — |
| Sage Investigational Site | North Canton | Ohio | 44720 | — |
| Sage Investigational Site | Oklahoma City | Oklahoma | 73112 | — |
| Sage Investigational Site | Plymouth Meeting | Pennsylvania | 19462 | — |
| Sage Investigational Site | Austin | Texas | 78759 | — |
| Sage Investigational Site | Dallas | Texas | 75231 | — |
| Sage Investigational Site | Houston | Texas | 77030 | — |
| Sage Investigational Site | Houston | Texas | 77081 | — |
| Sage Investigational Site | Wichita Falls | Texas | 76309 | — |
| Sage Investigational Site | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04476030, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 21, 2023 · Synced May 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04476030 live on ClinicalTrials.gov.