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Completed Phase 2 Interventional Results available

A Study of the Safety and Efficacy of SP-624 in the Treatment of Adults With Major Depressive Disorder

ClinicalTrials.gov ID: NCT04479852

Public ClinicalTrials.gov record NCT04479852. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 10, 2026, 4:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Efficacy of SP-624 in the Treatment of Adults With Major Depressive Disorder

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2 clinical study evaluating the safety and effectiveness of SP-624 as compared to placebo in the treatment of adults with Major Depressive Disorder.

Study identification

NCT ID
NCT04479852
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Sirtsei Pharmaceuticals, Inc.
Industry
Enrollment
319 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Sep 29, 2020
Primary completion
Jun 26, 2022
Completion
Aug 8, 2022
Last update posted
Jun 11, 2025

2020 – 2022

United States locations

U.S. sites
39
U.S. states
20
U.S. cities
39
Facility City State ZIP Site status
Alea Research Phoenix Arizona 85012
Woodland International Research Group Little Rock Arkansas 72211
Woodland Research Northwest Rogers Arkansas 72758
Collaborative Neuroscience Research Garden Grove California 92845
Pacific Research Partners Oakland California 94607
Artemis Institute for Clinical Research San Diego California 92103
Collaborative Neuroscience Research Torrance California 90502
MCB Clinical Research Centers Colorado Springs Colorado 80910
Sarkis Clinical Trials Gainesville Florida 32607
Clinical Neuroscience Solutions, Inc. Jacksonville Florida 32256
Innovative Clinical Research Lauderhill Florida 33319
Clinical Neuroscience Solutions, Inc. Orlando Florida 32801
Institute for Advanced Medical Research Alpharetta Georgia 30022
Atlanta Center for Medical Research Atlanta Georgia 30331
iResearch Atlanta Decatur Georgia 30030
American Medical Research Chicago Illinois 60612
Capstone Clinical Research Libertyville Illinois 60048
CBH Health Gaithersburg Maryland 20877
Midwest Research Group Saint Charles Missouri 63304
Altea Research Institute Las Vegas Nevada 89102
Hassman Research Institute Berlin New Jersey 08009
Center for Emotional Fitness Cherry Hill New Jersey 08002
Hassman Research Institute Marlton New Jersey 08053
SPRI Clinical Trials Brooklyn New York 11235
Manhattan Behavioral Medicine New York New York 10036
Richmond Behavioral Associates Staten Island New York 10312
New Hope Clinical Research Charlotte North Carolina 28211
Clinical Trials of America Hickory North Carolina 28601
Midwest Clinical Research Center Dayton Ohio 45417
Cutting Edge Research Group Oklahoma City Oklahoma 73116
Oregon Center for Clinical Investigations Portland Oregon 97214
Oregon Center for Clinical Investigations Salem Oregon 97301
Lehigh Center for Clinical Research Allentown Pennsylvania 18104
Clinical Neuroscience Solutions, Inc. Memphis Tennessee 38119
Donald J. Garcia, Jr., MD, PA Austin Texas 78737
Future Search Trials of Dallas Dallas Texas 75231
Red Oak Psychiatry Associates Houston Texas 77090
Grayline Research Center Wichita Falls Texas 76309
Core Clinical Research Everett Washington 98201

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04479852, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 11, 2025 · Synced Sep 10, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04479852 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →