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Terminated Phase 1 Interventional

Safety and Tolerability Study of Mivebresib Tablet Alone or in Combination With Ruxolitinib Tablet or Navitoclax Tablet in Adult Participants With Myelofibrosis

ClinicalTrials.gov ID: NCT04480086

Public ClinicalTrials.gov record NCT04480086. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 1:31 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1b Study of Mivebresib Alone or in Combination With Ruxolitinib or Navitoclax in Subjects With Myelofibrosis

Study identification

NCT ID
NCT04480086
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
AbbVie
Industry
Enrollment
1 participant

Conditions and interventions

Interventions

  • Mivebresib Drug
  • Navitoclax Drug
  • Ruxolitinib Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 16, 2021
Primary completion
Jul 27, 2023
Completion
Jul 27, 2023
Last update posted
Aug 28, 2023

2021 – 2023

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Stony Brook University Hospital /ID# 222653 Stony Brook New York 11794-8183
UC Health - Cincinnati /ID# 224079 Cincinnati Ohio 45267-2800
Thompson Cancer Survival Ctr /ID# 225802 Knoxville Tennessee 37916
University of Texas MD Anderson Cancer Center /ID# 221652 Houston Texas 77030

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04480086, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 28, 2023 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04480086 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →