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Completed Early Phase 1 Interventional

Smoking by IV Pulsed Nicotine

ClinicalTrials.gov ID: NCT04488744

Public ClinicalTrials.gov record NCT04488744. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 7:59 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Modeling Tobacco Smoking by IV Pulsed Nicotine in Smokers

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

To establish a dose-effect curve for nicotine's abuse potential as a function of nicotine dose and delivery rate. Pulsed IV nicotine administration will be used as it closely matches nicotine delivery by inhaled tobacco use.

Study identification

NCT ID
NCT04488744
Recruitment status
Completed
Study type
Interventional
Phase
Early Phase 1
Lead sponsor
Yale University
Other
Enrollment
13 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 35 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 15, 2019 (Actual)
Primary completion
Apr 28, 2021 (Actual)
Completion
May 31, 2021 (Actual)
Last update posted
Jul 20, 2021

2019 – 2021

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Veterans Affairs Hospital West Haven Connecticut 06516 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04488744, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 20, 2021 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT04488744 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →