Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer
Public ClinicalTrials.gov record NCT04489940. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter, Open Label Study of Bintrafusp Alfa (M7824) Monotherapy in Participants With HMGA2-expressing Triple Negative Breast Cancer
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study was to evaluate bintrafusp alfa monotherapy in participants with triple negative breast cancer (TNBC) who express high levels of HMGA2 as determined by a centralized reverse transcriptase-polymerase chain reaction (RT-PCR) test.
Study identification
- NCT ID
- NCT04489940
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 11 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 12, 2020 (Actual)
- Primary completion
- Jan 27, 2022 (Actual)
- Completion
- Jul 8, 2022 (Actual)
- Last update posted
- Apr 10, 2023
2020 – 2022
United States locations
- U.S. sites
- 15
- U.S. states
- 10
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Oncology Hematology Consultants, PA, Helen F. Graham Cancer Center, Suite 3400 | Newark | Delaware | 19713-2055 | — |
| Mayo Clinic-Jacksonville | Jacksonville | Florida | 32224 | — |
| Maryland Oncology Hematology, P.A. | Silver Spring | Maryland | 20904 | — |
| New York Oncology Hematology, P.C. - Albany | Albany | New York | 12206 | — |
| TheOhio State University, Stefanie Spielman Comprehensive Breast Center | Columbus | Ohio | 43212 | — |
| UPMC Hillman Cancer Center - Hillman Cancer Center | Monroeville | Pennsylvania | 15146 | — |
| Charleston Hematology Oncology Associates, PA | Charleston | South Carolina | 29414 | — |
| The West Clinic | Germantown | Tennessee | 38138 | — |
| Texas Oncology, P.A. - Austin - Austin Central Cancer Center | Austin | Texas | 78731 | — |
| Texas Oncology, P.A. - Medical City Dallas - Pediatric Hematology/Oncology | Dallas | Texas | 75230 | — |
| Texas Oncology, P.A. - Plano | Plano | Texas | 75075 | — |
| Texas Oncology-San Antonio Stone Oak | San Antonio | Texas | 78240 | — |
| Texas Oncology, P.A. - Tyler | Tyler | Texas | 75702 | — |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | — |
| Virginia Oncology Associates - Hampton | Norfolk | Virginia | 23502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 30 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04489940, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 10, 2023 · Synced Nov 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04489940 live on ClinicalTrials.gov.