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Completed Phase 2 Interventional Results available

B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

ClinicalTrials.gov ID: NCT04490109

Public ClinicalTrials.gov record NCT04490109. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 7:53 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Randomized, Double-Blind, Vehicle Controlled Study of the Efficacy, Safety, and Tolerability of B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a double-blind, randomized, vehicle-controlled study to assess the efficacy, safety, and tolerability of 2 doses of B244 for the treatment of pruritus in adults with a history of atopic dermatitis. Subjects who meet the study entry criteria will be randomized in a 1:1:1 ratio to receive twice daily topical doses of B244 O.D. 5.0, B244 O.D. 20.0, or vehicle (placebo) for 4 weeks.

Study identification

NCT ID
NCT04490109
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AOBiome LLC
Industry
Enrollment
547 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 65 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 23, 2020
Primary completion
Dec 9, 2021
Completion
Jan 6, 2022
Last update posted
Jan 27, 2025

2020 – 2022

United States locations

U.S. sites
56
U.S. states
27
U.S. cities
53
Facility City State ZIP Site status
Cahaba Dermatology Birmingham Alabama 35244
Elite Clinical Studies, LLC Phoenix Arizona 85018
Cognitive Clinical Trials Scottsdale Arizona 85260
Dermatology Trial Associates Bryant Arkansas 72022
Applied Research Center of Arkansas, Inc Little Rock Arkansas 72212
Core Healthcare Group Cerritos California 90703
Encino Research Center Encino California 91436
Center for Dermatology, INC Fremont California 94538
Antelope Valley Clinical Trials Lancaster California 93534
Long Beach Clinical Trials Services Long Beach California 90806
L.A. Universal Research Center Inc Los Angeles California 90057
Providence Clinical Research North Hollywood California 91606
Syrentis Clinical Research Santa Ana California 92705
IMMUNOe Research Centers Centennial Colorado 80112
Tampa Bay Medical Research Clearwater Florida 33761
Palm Beach Dermatology Group Delray Beach Florida 33484
South Coast Research Center, Inc Miami Florida 33136
D&H National Research Center Miami Florida 33155
Meridian International Research Miami Gardens Florida 33014
NAPA Research Pompano Beach Florida 33064
Clinical Research Trials of Florida, Inc Tampa Florida 33607
Moore Clinical Research Tampa Florida 33609
Medical Dermatology Associates of Chicago Chicago Illinois 60654
Clinical Investigation Specialists Libertyville Illinois 60048
Sneeze Wheeze & Itch Associates, LLC Normal Illinois 61761
Epiphany Dermatology Overland Park Kansas 66215
Meridian Clinical Research Baton Rouge Louisiana 70808
Continental Clinical Solutions Towson Maryland 21204
Oakland Hills Dermatology Auburn Hills Michigan 48326
Clarkston Dermatology Clarkston Michigan 48346
Onyx Clinical Reserach Flint Michigan 48507
mediSearch Clinical Trials Saint Joseph Missouri 64506
Thomas Dermatology Henderson Nevada 89052
JDR Dermatology Research, LLC Las Vegas Nevada 89148
ActivMed Practices & Research Portsmouth New Hampshire 03801
The Dermatology Group, P. C. Verona New Jersey 07044
Drug Trials Brooklyn Brooklyn New York 11230
Drug Trials America Hartsdale New York 10530
Saddick Research Group New York New York 10075
Dermatology Consulting Services, LLC High Point North Carolina 27262
Wake Research Raleigh North Carolina 27612
Clinical Research Solutions Cleveland Ohio 44130
Unity Clinical Research Oklahoma City Oklahoma 73118
Velocity Clinical Research Medford Oregon 97504
Dermdox Centers for Dematology Sugarloaf Pennsylvania 18249
Peak Research LLC Upper Saint Clair Pennsylvania 15241
Greater Providence Clinical Research Cranston Rhode Island 02920
AAPRI Research Warwick Rhode Island 02886
Omega Medical Research Warwick Rhode Island 02886
Dermatology & Laser Center of Charleston Charleston South Carolina 29407
Peak Research LLC Fort Mill South Carolina 29708
Clinical Research Solutions Milan Tennessee 38358
ACRC Trials Plano Texas 75024
Aspen Dermatology Orem Utah 84058
Advance Clinical Research Salt Lake City Utah 84117
Dominion Medical Associates Richmond Virginia 23219

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04490109, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 27, 2025 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04490109 live on ClinicalTrials.gov.

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