ClinicalTrials.gov record
Adaptive COVID-19 Treatment Trial 3 (ACTT-3)
ClinicalTrials.gov ID: NCT04492475
Public ClinicalTrials.gov record NCT04492475. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults (ACTT-3)
Study identification
- NCT ID
- NCT04492475
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 969 participants
Conditions and interventions
Conditions
Interventions
- Interferon beta-1a Drug
- Placebo Other
- Remdesivir Drug
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 4, 2020
- Primary completion
- Dec 20, 2020
- Completion
- Dec 20, 2020
- Last update posted
- Mar 13, 2022
2020
United States locations
- U.S. sites
- 55
- U.S. states
- 23
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham School of Medicine - Infectious Disease | Birmingham | Alabama | 35233 | — |
| UCSF Fresno Center for Medical Education and Research - Clinical Research Center | Fresno | California | 93701 | — |
| University of California San Diego Health - Jacobs Medical Center | La Jolla | California | 29037 | — |
| University of California Los Angeles Medical Center - Westwood Clinic | Los Angeles | California | 90095 | — |
| University of California Irvine Medical Center - Infectious Disease | Orange | California | 92868-3298 | — |
| VA Palo Alto Health Care System - Infectious Diseases | Palo Alto | California | 94304-1207 | — |
| Stanford University - Stanford Hospital and Clinics - Pediatrics - Infectious Diseases | Palo Alto | California | 94304-1503 | — |
| University of California Davis Medical Center - Internal Medicine - Infectious Disease | Sacramento | California | 95817-1460 | — |
| Naval Medical Center San Diego - Infectious Disease Clinic | San Diego | California | 92314 | — |
| University of California San Francisco - Zuckerberg San Francisco General Hospital - Division of HIV, ID, and Global Medicine | San Francisco | California | 94110-2859 | — |
| Cedars Sinai Medical Center | West Hollywood | California | 90048-1804 | — |
| Eastern Colorado Health Care System | Aurora | Colorado | 80045 | — |
| Denver Health Division of Hospital Medicine - Main Campus | Denver | Colorado | 80204 | — |
| University of Florida Health - Shands Hospital - Division of Infectious Diseases and Global Medicine | Gainesville | Florida | 32610 | — |
| University of Florida Health - Jacksonville - Department of Emergency Medicine | Jacksonville | Florida | 32209 | — |
| University of Miami Miller School of Medicine - Infectious Diseases | Miami | Florida | 33136 | — |
| Emory Vaccine Center - The Hope Clinic | Decatur | Georgia | 30030-1705 | — |
| Atlanta VA Medical Center - Infectious Diseases Clinic | Decatur | Georgia | 30033 | — |
| Tripler Army Medical Center (TAMC) | Honolulu | Hawaii | 96859 | — |
| Northwestern Hospital - Infectious Disease | Chicago | Illinois | 60611-2908 | — |
| University of Illinois at Chicago Division of Infectious Diseases | Chicago | Illinois | 60612 | — |
| University of Iowa Hospitals & Clinics - Department of Internal Medicine | Iowa City | Iowa | 52242 | — |
| Ochsner Medical Center - Kenner - Department of Infectious Diseases | Kenner | Louisiana | 70065 | — |
| Southeast Louisiana Veterans Health Care System - Section of Infectious Diseases | New Orleans | Louisiana | 70119 | — |
| University of Maryland School of Medicine - Center for Vaccine Development - Baltimore | Baltimore | Maryland | 21201 | — |
| Johns Hopkins Hospital - Medicine - Infectious Diseases | Baltimore | Maryland | 21287-0005 | — |
| Walter Reed National Military Medical Center | Bethesda | Maryland | 20889 | — |
| National Institutes of Health - Clinical Center, National Institute of Allergy and Infectious Diseases Laboratory Of Immunoregulation, Clinical Research Section | Bethesda | Maryland | 20892-1504 | — |
| Massachusetts General Hospital - Infectious Diseases | Boston | Massachusetts | 02114-2621 | — |
| University of Massachusetts Medical School - Infectious Diseases and Immunology | Worcester | Massachusetts | 01655-0002 | — |
| University of Minnesota Medical Center, Fairview - Infectious Diseases and International Medicine | Minneapolis | Minnesota | 55455-0356 | — |
| Saint Louis University - Center for Vaccine Development | St Louis | Missouri | 63104-1015 | — |
| University of Nebraska Medical Center - Infectious Diseases | Omaha | Nebraska | 68198-5400 | — |
| University of New Mexico Clinical and Translational Science Center | Albuquerque | New Mexico | 87106 | — |
| New York University School of Medicine - Langone Medical Center - Microbiology - Parasitology | New York | New York | 10016-6402 | — |
| University of Rochester Medical Center - Vaccine Research Unit | Rochester | New York | 14642-0001 | — |
| Montefiore Medical Center - Infectious Diseases | The Bronx | New York | 10467-2401 | — |
| Duke Human Vaccine Institute - Duke Vaccine and Trials Unit | Durham | North Carolina | 27704 | — |
| Womack Army Medical Center - Pulmonary and Respiratory Services | Fort Bragg | North Carolina | 28310 | — |
| Kaiser Permanente Northwest - Center for Health Research | Portland | Oregon | 97227 | — |
| Penn State Health Milton S. Hershey Medical Center - Division of Infectious Diseases | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania - Infectious Diseases | Philadelphia | Pennsylvania | 19104-4238 | — |
| Baylor Scott & White Health - Baylor University Medical Center - North Texas Infectious Disease Consultants | Dallas | Texas | 75246 | — |
| University of Texas Southwestern Medical Center - Internal Medicine - Infectious Diseases | Dallas | Texas | 75390-8884 | — |
| Brooke Army Medical Center | Fort Sam Houston | Texas | 78234 | — |
| University of Texas Medical Branch - Division of Infectious Disease | Galveston | Texas | 77555 | — |
| Baylor College of Medicine - Molecular Virology and Microbiology | Houston | Texas | 77030-3411 | — |
| Methodist Hospital - Houston | Houston | Texas | 77030 | — |
| University of Texas Health Science Center at San Antonio - Infectious Diseases | San Antonio | Texas | 78229-3901 | — |
| University of Utah - Infectious Diseases | Salt Lake City | Utah | 84132 | — |
| University of Virginia - Acute Care Surgery | Charlottesville | Virginia | 22908-0816 | — |
| Naval Medical Center Portsmouth - Infectious Disease Division | Portsmouth | Virginia | 23708 | — |
| EvergreenHealth Infectious Disease Service | Kirkland | Washington | 98034 | — |
| Providence Sacred Heart Medical Center | Spokane | Washington | 99204 | — |
| Madigan Army Medical Center - Infectious Disease Clinic | Tacoma | Washington | 98431 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04492475, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2022 · Synced Jul 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04492475 live on ClinicalTrials.gov.