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Withdrawn Phase 2 Interventional

Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma Participants

ClinicalTrials.gov ID: NCT04495010

Public ClinicalTrials.gov record NCT04495010. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 21, 2026, 9:30 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized Study of Neoadjuvant Nivolumab Plus Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab Plus Ipilimumab Followed by Either Adjuvant Nivolumab or Postsurgical Observation Depending on Pathologic Response Compared With Adjuvant Nivolumab in Treatment-Naive Patients With Resectable Clinically Detectable Stage III Melanoma

Study identification

NCT ID
NCT04495010
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 2
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
Not listed

Conditions and interventions

Conditions

Interventions

  • Nivolumab Biological
  • Ipilimumab Biological

Biological

Eligibility (public fields only)

Age range
12 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 30, 2021
Primary completion
Feb 27, 2024
Completion
Oct 22, 2027
Last update posted
Mar 18, 2021

2021 – 2027

United States locations

U.S. sites
23
U.S. states
17
U.S. cities
20
Facility City State ZIP Site status
Local Institution Gilbert Arizona 85234
Local Institution Tucson Arizona 85724
Local Institution San Francisco California 94158
Local Institution Aurora Colorado 80045
Local Institution Tampa Florida 33612
Local Institution Atlanta Georgia 30322
Local Institution Atlanta Georgia 30342
Local Institution Marietta Georgia 30060
Local Institution Annapolis Maryland 21401
Local Institution Boston Massachusetts 02114
Local Institution Boston Massachusetts 02215
Local Institution Minneapolis Minnesota 55407
Local Institution Minneapolis Minnesota 55455
Local Institution Hattiesburg Mississippi 39401
Local Institution St Louis Missouri 63110
Local Institution Morristown New Jersey 07960
Local Institution New Brunswick New Jersey 08901
Local Institution Cleveland Ohio 44195
Local Institution Portland Oregon 97239
Local Institution Houston Texas 77030
Local Institution Salt Lake City Utah 84112
Local Institution Charlottesville Virginia 22908
Local Institution Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 95 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04495010, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 18, 2021 · Synced Jul 21, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04495010 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →