AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension

ClinicalTrials.gov ID: NCT04499248

Public ClinicalTrials.gov record NCT04499248. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 5:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2 Study to Evaluate the Safety and Efficacy of AGN-193408 SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Study identification

NCT ID: NCT04499248
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 1, Phase 2
Lead sponsor: AbbVie; Industry
Enrollment: 96 participants

Conditions and interventions

Conditions

Interventions

AGN-193408 SR Drug
Lumigan Other
Lumigan Vehicle Other
Sham Administration Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 15, 2020
Primary completion: Jan 31, 2029
Completion: Jan 31, 2029
Last update posted: Mar 22, 2026

2020 – 2029

United States locations

U.S. sites: 42
U.S. states: 21
U.S. cities: 41

Facility	City	State	ZIP	Site status
Horizon Eye Specialists & Lasik Center - Sun City /ID# 252153	Sun City	Arizona	85351	Recruiting
Global Research Management /ID# 241699	Glendale	California	91204-2500	Recruiting
United Medical Research Institute /ID# 241701	Inglewood	California	90301	Completed
Lakeside Vision Center /ID# 241698	Irvine	California	92604	Recruiting
The Eye Research Foundation /ID# 234528	Newport Beach	California	92663-3637	Recruiting
Sacramento Eye Consultants /ID# 241697	Sacramento	California	95815	Recruiting
Premiere Practice Management LLC /ID# 235957	Torrance	California	90505	Completed
Wolstan & Goldberg Eye Associates /ID# 241700	Torrance	California	90505	Recruiting
Connecticut Eye Consultants P.C. /ID# 235862	Danbury	Connecticut	06810	Recruiting
Brandon Eye Associates - Brandon /ID# 276600	Brandon	Florida	33511	Recruiting
Nature Coast Clinical Research - Crystal River /ID# 237781	Crystal River	Florida	34429	Recruiting
Advanced Research, LLC /ID# 276987	Deerfield Beach	Florida	33064-1346	Recruiting
University of Florida Health Ophthalmology - Jacksonville /ID# 243122	Jacksonville	Florida	32209-6533	Completed
East Florida Eye Institute /ID# 235762	Stuart	Florida	34994	Recruiting
Logan Ophthalmic Research Inc. /ID# 252087	Tamarac	Florida	33321	Recruiting
Coastal Research Associates /ID# 234649	Roswell	Georgia	30076	Recruiting
Thomas Eye Group PC /ID# 266775	Sandy Springs	Georgia	30328	Completed
University of Illinois Hospital and Health Sciences System /ID# 253630	Chicago	Illinois	60607	Recruiting
Midwest Medical Advisors Inc /ID# 235845	Carmel	Indiana	46290	Completed
Indiana University - Glick Eye Institute /ID# 235887	Indianapolis	Indiana	46202	Completed
Ophthalmic Consultants of Boston /ID# 236535	Boston	Massachusetts	02129	Recruiting
Fraser Eye Care Center /ID# 267100	Fraser	Michigan	48026	Recruiting
Midwest Vision Research Foundation at Pepose Vision Institute /ID# 267094	Chesterfield	Missouri	63017	Recruiting
Silverstein Eye Centers /ID# 266767	Kansas City	Missouri	64133	Recruiting
Tekwani Vision Center /ID# 235149	St Louis	Missouri	63128	Completed
Nv Eye Surgery - Henderson /ID# 276925	Henderson	Nevada	89052	Recruiting
Rutgers New Jersey Medical School Campus, Doctors Office Center /ID# 234365	Newark	New Jersey	07103-2425	Completed
Northern New Jersey Eye Institute /ID# 241545	South Orange	New Jersey	07079	Recruiting
Asheville Eye Associates /ID# 234963	Asheville	North Carolina	28803	Completed
Private Practice - Dr. James D. Branch /ID# 234560	Winston-Salem	North Carolina	27101	Recruiting
The Ohio State University /ID# 267590	Columbus	Ohio	43210	Recruiting
Oklahoma Eye Surgeons /ID# 252089	Oklahoma City	Oklahoma	73112	Recruiting
Drs Fine Hoffman & Sims LLC /ID# 235919	Eugene	Oregon	97401	Completed
Scott and Christie and Associates /ID# 252284	Cranberry Township	Pennsylvania	16066	Completed
Eye Specialty Group /ID# 252201	Memphis	Tennessee	38120	Recruiting
Vanderbilt Eye Institute /ID# 266915	Nashville	Tennessee	37232-0025	Recruiting
Advancing Vision Research /ID# 236683	Smyrna	Tennessee	37167	Recruiting
Macro Trials (SMO/Network/Consortium) /ID# 266772	Austin	Texas	78731	Recruiting
San Antonio Eye Center /ID# 272087	San Antonio	Texas	78215	Recruiting
St. George Eye Center /ID# 236200	St. George	Utah	84790	Completed
Piedmont Eye Center /ID# 246455	Lynchburg	Virginia	24502	Recruiting
Vistar Eye Center /ID# 234811	Roanoke	Virginia	24011	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT04499248, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 22, 2026 · Synced May 20, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04499248 live on ClinicalTrials.gov.

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