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Completed Phase 2 Interventional

PN-943 in Adults With Moderate to Severe Active Ulcerative Colitis (UC)

ClinicalTrials.gov ID: NCT04504383

Public ClinicalTrials.gov record NCT04504383. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 7:31 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Double-blind, Placebo-controlled, Parallel-group, Multi-center Study to Evaluate the Safety and Efficacy of Oral PN-943 in Subjects With Moderate to Severe Active Ulcerative Colitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of the study is to evaluate the safety, tolerability, and clinical efficacy of PN-943 450 mg twice daily \[BID\] and PN-943 150 mg BID, compared with placebo BID, in subjects with moderate to severe active Ulcerative Colitis (UC).

Study identification

NCT ID
NCT04504383
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Protagonist Therapeutics, Inc.
Industry
Enrollment
169 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 4, 2020
Primary completion
Feb 15, 2023
Completion
Feb 15, 2023
Last update posted
Apr 24, 2023

2020 – 2023

United States locations

U.S. sites
31
U.S. states
17
U.S. cities
29
Facility City State ZIP Site status
Protagonist Investigational Site Tucson Arizona 85712
Protagonist Investigational Site Garden Grove California 92845
Protagonist Investigational Site Los Angeles California 90036
Protagonist Investigational Site Murrieta California 92563
Protagonist Investigational Site San Francisco California 94158
Protagonist Investigational Site Colorado Springs Colorado 80907
Protagonist Investigational Site Kissimmee Florida 34741
Protagonist Investigational Site Miami Florida 33125
Protagonist Investigational Site Miami Florida 33175
Protagonist Investigational Site Miami Florida 33180
Protagonist Investigational site Orlando Florida 32819
Protagonist Investigational Site Saint Augustine Florida 32086
Protagonist Investigational Site Wesley Chapel Florida 33544
Protagonist Investigational Site Metairie Louisiana 70006
Protagonist Investigational Site Glen Burnie Maryland 21061
Protagonist Investigational Site Chesterfield Michigan 48047
Protagonist Investigational Site Troy Michigan 48098
Protagonist Investigational Site Jackson Mississippi 39216
Protagonist Investigational Site St Louis Missouri 63110
Protagonist Investigational Site Englewood New Jersey 07631
Protagonist Investigational Site North Massapequa New York 11758
Protagonist Investigational Site Charlotte North Carolina 28210
Protagonist Investigational Site Norman Oklahoma 73071
Protagonist Investigational Site Oklahoma City Oklahoma 73103
Protagonist Investigational Site Orangeburg South Carolina 29118
Protagonist Investigational Site Nashville Tennessee 37212
Protagonist Investigational Site Austin Texas 78742
Protagonist Investigational site Garland Texas 75044
Protagonist Investigational Site Pasadena Texas 77505
Protagonist Investigational Site Spring Texas 77388
Protagonist Investigational site Lynchburg Virginia 24502

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 91 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04504383, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 24, 2023 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04504383 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →