Bucillamine in Treatment of Patients With COVID-19
Public ClinicalTrials.gov record NCT04504734. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study of Bucillamine in Patients With Mild-Moderate COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3, multi-center, randomized, double blind, placebo controlled, clinical study of bucillamine (2 dosage levels) in patients with mild-moderate COVID-19. Patients will be randomized 1:1:1 to receive bucillamine 100 mg 3 times a day (TID), bucillamine 200 mg TID or placebo TID for up to 14 days. After the first interim analysis when a single dose is selected, patients will then be randomized 1:1 to the selected bucillamine dose or placebo. This dose has now been chosen as 600 mg. The study will be overseen by an independent Data and Safety Monitoring Board (DSMB). Up to 50 centers in the United States will conduct this study. Up to 1000 patients will be enrolled in this study. Patients will participate in the study approximately 45 days.
Study identification
- NCT ID
- NCT04504734
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 713 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 27, 2020 (Actual)
- Primary completion
- Jun 12, 2023 (Actual)
- Completion
- Jun 12, 2023 (Actual)
- Last update posted
- Jul 7, 2023
2020 – 2023
United States locations
- U.S. sites
- 46
- U.S. states
- 15
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cullman Clinical Trials | Cullman | Alabama | 35055 | — |
| Avant Research Associates, LLC | Huntsville | Alabama | 35802 | — |
| West Valley Research Clinic | Phoenix | Arizona | 85031 | — |
| HealthStar Research LLC | Hot Springs | Arkansas | 71913 | — |
| ASCADA Research | Huntington Beach | California | 92648 | — |
| Samuel Ross MD Inc. | Los Angeles | California | 90035 | — |
| Amicis Research Center | Northridge | California | 91324 | — |
| Optimus Medical Group | San Francisco | California | 94102 | — |
| C & R Research Services USA | Coral Gables | Florida | 33134 | — |
| Sweet Hope Research Specialty Inc | Hialeah | Florida | 33016 | — |
| Encore Medical Research | Hollywood | Florida | 33021 | — |
| Entrust Clinical Research | Kendall | Florida | 33156 | — |
| Columbus Clinical Services | Miami | Florida | 33125 | — |
| Verus Clinical Research | Miami | Florida | 33125 | — |
| Nuren Medical & Research Center | Miami | Florida | 33144 | — |
| Advance Medical Research Services Corp | Miami | Florida | 33165 | — |
| Amavita Clinical Research | North Miami Beach | Florida | 33169 | — |
| C & R Research Services USA | Tampa | Florida | 33614 | — |
| Encore Medical Research of Weston LLC | Weston | Florida | 33321 | — |
| Clinical Site Partners LLC | Winter Park | Florida | 32789 | — |
| American Clinical Trials LLC | Acworth | Georgia | 30101 | — |
| Quad Clinical Research LLC | Chicago | Illinois | 60643 | — |
| Koch Family Medicine | Morton | Illinois | 61550 | — |
| Revive Research Institute Inc. | Farmington Hills | Michigan | 48334 | — |
| SRI International | Plymouth | Michigan | 48170 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075 | — |
| Revival Research Institute LLC | Sterling | Michigan | 48312 | — |
| Machuca Family Medicine | Las Vegas | Nevada | 89104 | — |
| Prime Global Research | The Bronx | New York | 10456 | — |
| OnSite Clinical Solutions | Charlotte | North Carolina | 28208 | — |
| OnSite Clinical Solutions, LLC | Charlotte | North Carolina | 28277 | — |
| Monroe Biomedical Research | Monroe | North Carolina | 28112 | — |
| Superior Clinical Research | Smithfield | North Carolina | 27577 | — |
| Superior Clinical Research | Yanceyville | North Carolina | 27379 | — |
| Dayton Clinical Research | Dayton | Ohio | 45406 | — |
| Pharmacorp Clinical Trials Inc. | Charleston | South Carolina | 29412 | — |
| Novaceut Clinical Research | Clarksville | Tennessee | 37043 | — |
| Physicians Quality Care | Jackson | Tennessee | 38305 | — |
| Inquest Clinical Research | Baytown | Texas | 77521 | — |
| C & R Research Services USA | Houston | Texas | 77022 | — |
| Encore Imaging and Medical Research | Houston | Texas | 77065 | — |
| R & H Clinical Research Inc. | Katy | Texas | 77494 | — |
| FMC Science | Lampasas | Texas | 76550 | — |
| Family Practice Center | McAllen | Texas | 78501 | — |
| R & H Clinical Research Inc. | Stafford | Texas | 77477 | — |
| Renovatio Clinical | The Woodlands | Texas | 77380 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04504734, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 7, 2023 · Synced Oct 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04504734 live on ClinicalTrials.gov.