A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain
Public ClinicalTrials.gov record NCT04504812. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Study identification
- NCT ID
- NCT04504812
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Johns Hopkins University
- Other
- Enrollment
- 1,937 participants
Conditions and interventions
Conditions
Interventions
- Best Practices Other
- Duloxetine Drug
- Intra-Articular Injection Combination Product
- Nerve Procedure with long acting blocks Procedure
- Nerve Procedure with nerve ablation Procedure
- Pain Coping Skills Training Behavioral
Other · Drug · Combination Product + 2 more
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2021
- Primary completion
- Apr 7, 2025
- Completion
- Apr 7, 2025
- Last update posted
- Apr 8, 2026
2021 – 2025
United States locations
- U.S. sites
- 24
- U.S. states
- 17
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California Davis | Sacramento | California | 95817 | — |
| University of California San Diego | San Diego | California | 92037 | — |
| VA Medical Center San Diego | San Diego | California | 92161 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Emory University | Atlanta | Georgia | 30322 | — |
| Atlanta VA Medical Center | Decatur | Georgia | 30033 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Johns Hopkins | Baltimore | Maryland | 21287 | — |
| Walter Reed Army Medical Center | Bethesda | Maryland | 20889 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02199 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Weill Cornell University | New York | New York | 10019 | — |
| University of Rochester Medical Center | Rochester | New York | 14623 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | — |
| Wake Forest University | Winston-Salem | North Carolina | 27517 | — |
| Cleveland VA Medical Center | Cleveland | Ohio | 44106 | — |
| University Hospitals | Cleveland | Ohio | 44106 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Vanderbilt University | Nashville | Tennessee | 37232 | — |
| University of Utah | Salt Lake City | Utah | 84108 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| University of Washington | Seattle | Washington | 98185 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04504812, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 8, 2026 · Synced May 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04504812 live on ClinicalTrials.gov.