ClinicalTrials.gov record
A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-Mediated COVID-19 in Adult Participants
ClinicalTrials.gov ID: NCT04505722
Public ClinicalTrials.gov record NCT04505722. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older
Study identification
- NCT ID
- NCT04505722
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Vaccines & Prevention B.V.
- Industry
- Enrollment
- 44,325 participants
Conditions and interventions
Interventions
- Ad26.COV2.S Biological
- Placebo Other
Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 6, 2020
- Primary completion
- Mar 30, 2023
- Completion
- Mar 30, 2023
- Last update posted
- Feb 3, 2025
2020 – 2023
United States locations
- U.S. sites
- 117
- U.S. states
- 31
- U.S. cities
- 80
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Synexus Clinical Research US Inc | Birmingham | Alabama | 35209 | — |
| University of Alabama Birmingham | Birmingham | Alabama | 35233 | — |
| Alabama Vaccine Research Clinic at UAB | Birmingham | Alabama | 35294 | — |
| Optimal Research | Huntsville | Alabama | 35802 | — |
| Synexus Clinical Research US Inc | Glendale | Arizona | 85308 | — |
| VA Medical Center | Phoenix | Arizona | 85012 | — |
| Central Phoenix Medical Clinic | Phoenix | Arizona | 85020 | — |
| Quality of Life Medical & Research Center, LLC | Tucson | Arizona | 85712 | — |
| Synexus Clinical Research US Inc | Tucson | Arizona | 85712 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72202 | — |
| Central Arkansas Veterans Healthcare System | Little Rock | Arkansas | 72205 | — |
| Anaheim Clinical Trials, LLC | Anaheim | California | 92801 | — |
| Ark Clinical Research | Long Beach | California | 90806 | — |
| Anthony Mills Medical, Inc | Los Angeles | California | 90069 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| UCSD Antiviral Research Center AVRC | San Diego | California | 92103 | — |
| Wr McCr Llc | San Diego | California | 92108 | — |
| VA Medical Center | San Francisco | California | 94121-1545 | — |
| Childrens Hospital Colorado | Aurora | Colorado | 80045 | — |
| Rocky Mountain Regional VA Medical Center | Denver | Colorado | 80220 | — |
| Avail Clinical Research, LLC | DeLand | Florida | 32720 | — |
| North Florida South Georgia Veteran Health System | Gainesville | Florida | 32608 | — |
| Velocity Clinical Research, Hallandale Beach | Hallandale | Florida | 33009 | — |
| Research Centers of America, LLC | Hollywood | Florida | 33024 | — |
| Suncoast Research Group | Miami | Florida | 33135 | — |
| University of Miami - Miller School of Medicine | Miami | Florida | 33136 | — |
| Orlando Immunology Center | Orlando | Florida | 32803 | — |
| Advent Health Orlando | Orlando | Florida | 32804 | — |
| Synexus Clinical Research US Inc | Orlando | Florida | 32806 | — |
| Synexus Clinical Research US Inc | Pinellas Park | Florida | 33781 | — |
| James A Haley VA Hospital GNS | Tampa | Florida | 33612 | — |
| Synexus Clinical Research US Inc | The Villages | Florida | 32162 | — |
| Emory University of Medicine | Atlanta | Georgia | 30322 | — |
| The Hope Clinic at Emory University | Decatur | Georgia | 30030-1705 | — |
| Atlanta VA Medical Center | Decatur | Georgia | 30033 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| Jesse Brown VAMC Department of Surgery | Chicago | Illinois | 60612 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| University of IL Chicago | Chicago | Illinois | 60612 | — |
| The University Of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Optimal Research | Peoria | Illinois | 61614 | — |
| Buynak Clinical Research | Valparaiso | Indiana | 46383 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219 | — |
| Central Kentucky Research Associates, Inc. | Lexington | Kentucky | 40509 | — |
| University of Kentucky | Lexington | Kentucky | 40536 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Benchmark Research | Metairie | Louisiana | 70006 | — |
| Clinical Trials Management, LLC | Metairie | Louisiana | 70006 | — |
| New Orleans Adolescent Trials Unit CRS | New Orleans | Louisiana | 70118 | — |
| Southeast Louisiana Veterans Health Care Center | New Orleans | Louisiana | 70119 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Baltimore VA Medical Center | Baltimore | Maryland | 21201 | — |
| Optimal Research | Rockville | Maryland | 20850 | — |
| Meridian Clinical Research, LLC | Rockville | Maryland | 20854 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| The Brigham and Women's Hospital, Inc. | Boston | Massachusetts | 02115 | — |
| University of Michigan Neuorsurgery A. Alfred Taubman Health Care Center | Ann Arbor | Michigan | 48109-5000 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Cherry Street Services, Inc. | Grand Rapids | Michigan | 49503 | — |
| Abbott Northwestern Hospital Clinic | Minneapolis | Minnesota | 55407 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| MediSync Clinical Research | Petal | Mississippi | 39465 | — |
| The Center For Pharmaceutical Research | Kansas City | Missouri | 64114 | — |
| Saint Louis University | St Louis | Missouri | 63106 | — |
| Washington University School Of Medicine | St Louis | Missouri | 63110-1035 | — |
| Synexus Clinical Research US Inc | St Louis | Missouri | 63141 | — |
| Clinical Research Center of Nevada | Las Vegas | Nevada | 89106 | — |
| Clinical Research Consortium, an AMR company | Las Vegas | Nevada | 89119 | — |
| VA Sierra Nevada Health Care System | Reno | Nevada | 89509 | — |
| Rutgers Robert Wood Johnson Medical School | New Brunswick | New Jersey | 08903 | — |
| Saint Michaels Medical Center | Newark | New Jersey | 07102 | — |
| Raymond G. Murphy VA Medical Center | Albuquerque | New Mexico | 87108 | — |
| Meridian Clinical Research, LLC | Endwell | New York | 13760 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Harlem Hospital Center | New York | New York | 10037 | — |
| New York Blood Center | New York | New York | 10065 | — |
| Rochester Clinical Research, Inc | Rochester | New York | 14609 | — |
| Bronx Veterans Affairs Medical Center | The Bronx | New York | 10468 | — |
| Tryon Medical Group | Charlotte | North Carolina | 28210 | — |
| Carolina Institute for Clinical Research | Fayetteville | North Carolina | 28304 | — |
| Durham VAMC | Raleigh | North Carolina | 27610 | — |
| Wake Research Associates | Raleigh | North Carolina | 27612 | — |
| Wake Forest Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Synexus Clinical Research US Inc | Akron | Ohio | 44311 | — |
| CTI Clinical Trial and Consulting Services | Cincinnati | Ohio | 45212 | — |
| Synexus Clinical Research US Inc | Cincinnati | Ohio | 45236 | — |
| Velocity Clinical Research | Cincinnati | Ohio | 45242 | — |
| Rapid Medical Research | Cleveland | Ohio | 44122 | — |
| Synexus Clinical Research US Inc | Columbus | Ohio | 43212 | — |
| Corvallis Clinic PC | Corvallis | Oregon | 97330 | — |
| Clinical Research Institute of Southern Oregon, P.C. | Medford | Oregon | 97504 | — |
| Oregon Health And Science University | Portland | Oregon | 97239 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| University of Pittsburgh | Pittsburgh | Pennsylvania | 15232 | — |
| Synexus Clinical Research US Inc | Anderson | South Carolina | 29621-2062 | — |
| VA Medical Center | Columbia | South Carolina | 29201 | — |
| Coastal Carolina Research Center | Mt. Pleasant | South Carolina | 29464 | — |
| PMG Research of Charleston, LLC | Mt. Pleasant | South Carolina | 29464 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| St Jude Children's Research Hospital | Memphis | Tennessee | 38105 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Benchmark Research | Austin | Texas | 78705 | — |
| Optimal Research, LLC | Austin | Texas | 78705 | — |
| AIDS Arms Incorporated Trinity Health and Wellness Center | Dallas | Texas | 75208 | — |
| Synexus Clinical Research US Inc | Dallas | Texas | 75234 | — |
| Baylor Scott and White Research Institute | Dallas | Texas | 75246 | — |
| North Texas Infectious Diseases Consultants | Dallas | Texas | 75246 | — |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Texas Center for Drug Development Inc | Houston | Texas | 77081 | — |
| Gordon Crofoot, MD | Houston | Texas | 77098 | — |
| Clinical Trials of Texas Inc | San Antonio | Texas | 78229 | — |
| Synexus Clinical Research US Inc | San Antonio | Texas | 78229 | — |
| Synexus Clinical Research US Inc | Murray | Utah | 84123 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Advanced Clinical Research | West Jordan | Utah | 84088 | — |
| Kaiser Permanente Washington Health Research Institute | Seattle | Washington | 98101 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 108 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04505722, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 3, 2025 · Synced Jul 22, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT04505722 live on ClinicalTrials.gov.