ClinicalTrials.gov record
Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE
ClinicalTrials.gov ID: NCT04505774
Public ClinicalTrials.gov record NCT04505774. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic and Additional Strategies in Hospitalized Adults With COVID-19
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, open label, adaptive platform trial to compare the effectiveness of antithrombotic and additional strategies for prevention of adverse outcomes in COVID-19 positive inpatients
Study identification
- NCT ID
- NCT04505774
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 4
- Enrollment
- 3,591 participants
Conditions and interventions
Conditions
Interventions
- theraputic heparin Drug
- prophylactic heparin Drug
- P2Y12 Drug
- Crizanlizumab Injection Drug
- SGLT2 inhibitor Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 4, 2020 (Actual)
- Primary completion
- Aug 31, 2023 (Actual)
- Completion
- Jan 26, 2024 (Actual)
- Last update posted
- Dec 30, 2024
2020 – 2024
United States locations
- U.S. sites
- 81
- U.S. states
- 33
- U.S. cities
- 68
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama | Birmingham | Alabama | 35233 | — |
| University of Arizona | Tucson | Arizona | 85719 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| Kaiser Permanente Fontana | Fontana | California | 92335 | — |
| Kaiser Permanente Los Angeles | Los Angeles | California | 90027 | — |
| Smidt Heart Institute at Cedars-Sinai | Los Angeles | California | 90048 | — |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | — |
| UC San Diego Hillcrest | San Diego | California | 92103 | — |
| Zuckerberg San Francisco General Hospital | San Francisco | California | 94110 | — |
| UCSF San Francisco | San Francisco | California | 94143 | — |
| Zuckerberg San Francisco General Hospital | San Francisco | California | 94410 | — |
| Stanford University Medical Center | Stanford | California | 94305 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | Torrance | California | 90502 | — |
| Denver Health and Hospital Authority | Denver | Colorado | 80401 | — |
| St. Mary's Hospital & Regional Medical Center | Grand Junction | Colorado | 81501 | — |
| Saint Francis Hospital and Medical Center | Hartford | Connecticut | 06105 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Memorial Hospital | Jacksonville | Florida | 32216 | — |
| AdventHealth Tampa | Tampa | Florida | 33613 | — |
| Emory | Atlanta | Georgia | 30308 | — |
| Morehouse School of Medicine | Atlanta | Georgia | 30310 | — |
| Queens Medical Center | Honolulu | Hawaii | 96813 | — |
| Memorial Hospital | Belleville | Illinois | 62226 | — |
| Cook County Health | Chicago | Illinois | 60612 | — |
| University of Illinois at Chicago Health (UIH) | Chicago | Illinois | 60612 | — |
| OSF Little Company of Mary Medical Center (OSF LCM) | Evergreen Park | Illinois | 60805 | — |
| Indiana University Health Methodist Hospital | Indianapolis | Iowa | 46202 | — |
| Kansas University Medical Center | Kansas City | Kansas | 66160 | — |
| Ochsner Clinic Foundation | New Orleans | Louisiana | 70121 | — |
| Boston University | Boston | Massachusetts | 02118 | — |
| St Elizabeth's Medical Center | Brighton | Massachusetts | 02135 | — |
| Baystate Medical Center | Springfield | Massachusetts | 01199 | — |
| University of Massachusetts | Worcester | Massachusetts | 01655 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Wayne State University | Detroit | Michigan | 48201 | — |
| Hennepin County Medical Center | Minneapolis | Minnesota | 55415 | — |
| University of Mississippi Medical Center | Jackson | Mississippi | 39216 | — |
| Washington University School of Medicine, ACCS Research | St Louis | Missouri | 63110 | — |
| University Medical Center of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Cooper Health | Camden | New Jersey | 08103 | — |
| Englewood Health | Englewood | New Jersey | 07631 | — |
| Atlantic Health System | Morristown | New Jersey | 07960 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07103 | — |
| AtlantiCare Regional Medical Center | Pomona | New Jersey | 08240 | — |
| Albany Medical College | Albany | New York | 12208 | — |
| Mercy Hospital Buffalo | Buffalo | New York | 14220 | — |
| VA New York Harbor Healthcare System | New York | New York | 10010 | — |
| NYU Langone | New York | New York | 10016 | — |
| Mt. Sinai Hospital | New York | New York | 10029 | — |
| SUNY Upstate University Hospital | Syracuse | New York | 13210 | — |
| Jacobi Medical Center | The Bronx | New York | 10461 | — |
| Montefiore Medical Center | The Bronx | New York | 10461 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Duke University Hospital | Durham | North Carolina | 27704 | — |
| Wake Forest | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic Akron General | Akron | Ohio | 44307 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | — |
| The MetroHealth System | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| Ohio State Universtiy Wexner Medical Center | Columbus | Ohio | 43210 | — |
| Mercy Health St Vincent Medical Center | Toledo | Ohio | 43608 | — |
| Ascension St. John Clinical Research Institute | Tulsa | Oklahoma | 74104 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Geisinger Research | Danville | Pennsylvania | 17822 | — |
| Doylestown Cardiology Associates | Doylestown | Pennsylvania | 18901 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Hospital of the University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Temple University | Philadelphia | Pennsylvania | 19141 | — |
| UPMC Presbyterian | Pittsburgh | Pennsylvania | 15260 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| The Miriam Hospital | Providence | Rhode Island | 02906 | — |
| Sarah Cannon and HCA Research Institute | Nashville | Tennessee | 37203 | — |
| Skyline Medical Center | Nashville | Tennessee | 37207 | — |
| University of Texas at Austin | Austin | Texas | 78701 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Medical City Ft Worth | Fort Worth | Texas | 76104 | — |
| Baylor Scott and White Medical Center - Temple | Temple | Texas | 76508 | — |
| HCA Henrico Doctors Hospital | Richmond | Virginia | 23229 | — |
| Swedish Hospital | Seattle | Washington | 98122 | — |
| West Virginia University CTR | Morgantown | West Virginia | 26506 | — |
| University of Wisconsin Hospital; Meriter Hospital (UW affiliated) | Madison | Wisconsin | 53715 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 20 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT04505774, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 30, 2024 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT04505774 live on ClinicalTrials.gov.