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Recruiting No phase listed Observational

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

ClinicalTrials.gov ID: NCT04509050

Public ClinicalTrials.gov record NCT04509050. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 20, 2026, 7:13 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Prospective Study to Evaluate Biological and Clinical Effects of Significantly Corrected CFTR Function in Infants and Young Children (BEGIN Study)

Study identification

NCT ID
NCT04509050
Recruitment status
Recruiting
Study type
Observational
Phase
Not listed
Lead sponsor
Sonya Heltshe
Other
Enrollment
210 participants

Conditions and interventions

Interventions

  • Ivacaftor or elexacaftor/tezacaftor/ivacaftor Drug

Drug

Eligibility (public fields only)

Age range
Up to 10 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 17, 2020
Primary completion
Dec 30, 2027
Completion
Dec 30, 2027
Last update posted
Jul 7, 2026

2020 – 2027

United States locations

U.S. sites
35
U.S. states
22
U.S. cities
34
Facility City State ZIP Site status
The Children's Hospital Alabama, University of Alabama at Birmingham Birmingham Alabama 35233 Recruiting
Stanford University Medical Center Palo Alto California 94304 Recruiting
Children's Hospital Colorado Aurora Colorado 80045 Recruiting
Nemours Children's Clinic Jacksonville Florida 32207 Recruiting
University of Miami Miami Florida 33136 Recruiting
The Nemours Children's Clinic - Orlando Orlando Florida 32827 Recruiting
Riley Hospital for Children Indianapolis Indiana 46202 Recruiting
University of Iowa Iowa City Iowa 52242 Recruiting
University of Kansas Medical Center Kansas City Kansas 66160 Recruiting
Boston Children's Hospital Boston Massachusetts 02115 Recruiting
University of Michigan, Michigan Medicine Ann Arbor Michigan 48109 Recruiting
Helen DeVos Children's Hospital Grand Rapids Michigan 49503 Recruiting
Children's Hospitals and Clinics of Minnesota Minneapolis Minnesota 55404 Recruiting
The Minnesota Cystic Fibrosis Center Minneapolis Minnesota 55455 Recruiting
Children's Mercy Kansas City Kansas City Missouri 64108 Recruiting
St. Louis Children's Hospital St Louis Missouri 63110 Recruiting
The Cystic Fibrosis Center of Western New York Buffalo New York 14203 Recruiting
Children's Hospital of New York New York New York 10032 Recruiting
SUNY Upstate Medical University Syracuse New York 13210 Recruiting
New York Medical College at Westchester Medical Center Valhalla New York 10595 Recruiting
Cincinnati Children's Hospital Medical Center Cincinnati Ohio 45229 Recruiting
Nationwide Children's Hospital Columbus Ohio 43205 Recruiting
Oklahoma Cystic Fibrosis Center Oklahoma City Oklahoma 73104 Recruiting
Oregon Health Sciences University Portland Oregon 97239 Recruiting
Hershey Medical Center Pennsylvania State University Hershey Pennsylvania 17033 Recruiting
Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104 Recruiting
Children's Hospital of Pittsburgh of UPMC Pittsburgh Pennsylvania 15224 Recruiting
University of Texas Southwestern / Children's Health Dallas Texas 75207 Recruiting
Cook Children's Medical Center Fort Worth Texas 76104 Recruiting
Baylor College of Medicine Houston Texas 77030 Recruiting
Primary Children's Cystic Fibrosis Center Salt Lake City Utah 84113 Recruiting
Vermont Children's Hospital Burlington Vermont 05401 Recruiting
University of Virginia Charlottesville Virginia 22903 Recruiting
Seattle Children's Hospital Seattle Washington 98105 Recruiting
University of Wisconsin Madison Wisconsin 53792 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT04509050, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 7, 2026 · Synced Jul 20, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT04509050 live on ClinicalTrials.gov.

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